Glycolysis

Rita Ferreira has a degree and a PhD in Biochemistry. RF is Assistant Professor at University of Aveiro where she has been teaching courses related to biochemistry and biomedicine to both undergraduate and graduate students. RF develops research work in the field of muscle plasticity in pathophysiological conditions, including the evaluation of the impact of exercise training in cancer-induced muscle wasting using Omics approaches. She is particularly interested in the study of the preventive and therapeutic effect of physical activity in the setting of wasting conditions. Dr. Pedro Fontes Oliveira, in 2004, earned his PhD degree in Biomedical Sciences, at the University of Porto, Portugal. In 2005, Pedro F. Oliveira started his post-doctoral fellowship at the University of Porto and began working on a new line of research now focused on reproductive biology, specifically in Sertoli cells ionic regulation. In 2009, Dr. Oliveira was selected to apply for the “Ciência 2008 Program” through the Health Science Research Center, University of Beira Interior (CICS-UBI) and was hired as an Assistant Researcher. Currently Dr. Oliveira's research interests include hormonal control and metabolic modulation of spermatogenesis, with emphasis on Sertoli cells hormonal modulation, ionic water transport, and mechanisms by which endocrine disorders and pathologies, namely Diabetes Mellitus, result in subfertility and infertility. Rita Nogueira Ferreira has a graduation in Biochemistry (2010), a master's degree in Biochemistry – specialization in Clinical Biochemistry (2012), and a PhD in Biochemistry (2017), obtained at the University of Aveiro (Portugal). She has been developing research work in the study of the molecular and cellular mechanisms associated with different pathological conditions (pulmonary arterial hypertension, heart failure, cancer, obesity) and related to the effect of pharmacological and non-pharmacological approaches (exercise training) in the prevention or treatment of these conditions, using proteomic approaches. Currently, she works as Junior Researcher at UnIC@RISE, Department of Surgery and Physiology from the Faculty of Medicine of the University of Porto, Portugal. She was awarded in the FCT Individual Call to Scientific Employment Stimulus (CEECIND) 2021 to proceed in the study of sexual dimorphism in cardiovascular pathophysiology. In particular, she is interested in exploring the sex differences in heart failure, as well as the adaptations to exercise training, aiming to improve heart failure management.

• PART I GLYCOLYSIS AND PHYSIOLOGICAL PROCESSES1. Development and glycolysis dependence2. Neuro-glia communication and glycolysis3. Glycolysis and skeletal muscle plasticity4. Glycolysis and trained heart5. Bone glycolysis and the regulation of energy balance6. Glycolysis in adipose tissue-dependent thermogenesis7. Regulation of glycolysis from a liver-centric perspective 8. Glycolysis as a rheostat mechanism in pancreas function9. The Warburg-like effect in reproductive eventsPART II GLYCOLYSIS AND PATHOLOGICAL EVENTS 10. Exploring glycolytic adaptations in cancer cells11. The glycolytic pathway to heart failure12. Glycolysis in PAH and COPD metabolic reprogramming13. Glycolysis and mitochondrial function in diabetes mellitus 14. Metabolic adaptation to glycolysis as a basic defense mechanism of immune cells15. Inborn glycolytic pathway defects16. Enhanced glycolysis and metabolic complications of hematologic malignancies17. Implications of glycolysis for osteoporosis pathogenesis18. Glucose, glycolysis, and neurodegenerative diseases19. Viral Infections and glycolysisSUPPLEMENTAL INFORMATION – Methodological approaches20. The application of Omics to explore glycolysis 21. An interactive analysis of glycolysis regulation22. Measuring glycolysis flux