Fundamentals of Molecular Structural Biology

Nyhet

Häftad, Engelska, 2026

AvSubrata Pal

2 059 kr

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Häftad

1 509 kr

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Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.

Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

Explores AI contributions to the study of molecular structural biology, from fundamental concepts to applications
Describes the latest techniques and approaches in the field, including cryo-electron tomography and nuclear magnetic resonance
Provides a current and easily digestible resource on molecular structural biology, discussing both foundations and the latest advances
Addresses critical issues surrounding macromolecular structures, such as structure-based drug discovery, single-particle analysis, computational molecular biology/molecular dynamic simulation, cell signaling and immune response, macromolecular assemblies, and systems biology
Presents discussions that ultimately lead the reader toward a more detailed understanding of the basis and origin of disease

Produktinformation

Utgivningsdatum2026-05-01
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor650
Upplaga2
FörlagElsevier Science
ISBN9780443339806

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik

Subrata Pal obtained his bachelor’s and master’s degrees, both in physics, from Calcutta University. Subsequently, he pursued his predoctoral research in molecular biology and received a PhD degree from the same university in 1982. He carried out his postdoctoral research in DNA replication and gene expression at two of the premiere institutions in the USA: the National Institutes of Health, Bethesda, Maryland and Harvard Medical School, Boston Massachusetts. At Harvard, he received a Claudia Adams Barr special investigator award for basic contribution to cancer research. Professor Pal has a long teaching experience at the undergraduate and graduate levels – the areas of his teaching include physics, molecular biology and genomics.

1. Introduction: A historical perspective2. Mathematical preliminaries3. Physical basis of chemistry4. Chemical basis of biology5. Biomacromolecules6. Structure analysis and visualization7. Protein Folding8. DNA synthesis: Replication9. Transcription10. RNA processing11. Translation12. DNA damage and repair13. Recombination14. Membrane structure and function15. Fundamentals of structural genomics16. Cell signaling and systems biology17. Macromolecular assemblies18. Computational molecular biology19. Artificial intelligence (AI) applications