Equine Laminitis

James K. Belknap, DVM, PhD, Diplomate ACVS, is Professor of Equine Surgery in the Department of Veterinary Clinical Sciences at Ohio State University in Columbus, Ohio, USA.  He runs a research laboratory studying the pathophysiology of equine laminitis, and works closely with the Certified Journeyman Farrier, Todd Adams, on podiatry cases including equine laminitis cases.

• Contributors viiForeword xAbbreviations xiiPart 1: Overview: From Basic Research to Caring for the Laminitis Patient1 Historical Perspective on Equine Laminitis 3Donald M. Walsh and Teresa A. Burns2 Laminitis: An Overview 11James K. Belknap3 Anatomy and Function of the Equine Digit 13A.H. Parks4 Lamellar Function at the Cellular Level 22Christopher C. Pollitt5 Digital Biomechanics Relevant to Laminitis 39Jonathan Merritt, Helen Davies and Andrew H. ParksPart 2: Pathophysiology of Laminitis6 Overview 51James K. Belknap7 Experimental Models of Laminitis: Starch Overload 54Susan C. Eades8 Experimental Models of Laminitis: Oligofructose Overload 59Christopher C. Pollitt and Gabriel J. Milinovich9 Experimental Models of Laminitis: Black Walnut Extract 64John F. Peroni10 Experimental Models of Laminitis: Hyperinsulinemia 68Catherine McGowan and Janet Patterson-Kane11 Hemodynamic Events in Laminitis 75John F. Peroni, Susan C. Eades and Simon R. Bailey12 The Role of Thrombosis and Coagulation in Equine Laminitis 82Simon R. Bailey13 Leukocytes and Inflammatory Signaling in Laminitis: Leukocytes 91Rafael R. Faleiros and James K. Belknap14 Leukocytes and Inflammatory Signaling in Laminitis: Inflammatory Signaling 102Britta Leise15 Role of Proteases in Laminitis 115Samuel J. Black, Le Wang, Erica Pawlak, Fengqiu Zhang, John Loftus and Dominique Alfandari16 Endocrine and Metabolic Dysregulation in Laminitis: Role of Pituitary Dysfunction 134Philip J. Johnson17 Endocrine and Metabolic Dysregulation in Laminitis: Role of Corticosteroids 141Philip J. Johnson18 Metabolic Syndrome in Humans and Horses: The Relationship Between Obesity and Insulin Resistance 149Teresa A. Burns and Ramiro E. Toribio19 Dysregulation of the Lamellar Basal Epithelial Cell in Laminitis: Role of the Cytoskeleton and Cell Junctions 167Christopher C. Pollitt20 Structural Dynamics of Displacement of the Distal Phalanx 176Andrew H. ParksPart 3: Clinical Presentation of Equine Laminitis21 General Clinical Aspects of the Laminitis Case 183Andrew van Eps22 Sepsis-Related Laminitis 191Susan C. Eades23 Laminitis in Equine Metabolic Syndrome 196Andy E. Durham24 Laminitis in Pituitary Pars Intermedia Dysfunction 204Philip J. Johnson25 Supporting Limb Laminitis 210Gary M. BaxterPart 4: Diagnostic Evaluation of Equine Laminitis26 Detailed Physical Examination for Laminitis 217Richard A. Mansmann and Hans H. Castelijns27 Diagnostic Imaging 226Andrew H. Parks and James K. Belknap28 The Digital Venogram 240Amy Rucker29 Endocrine and Metabolic Evaluation in Horses with Laminitis 252Ramiro E. Toribio and Teresa A. BurnsPart 5: Medical Treatment of the Laminitic Patient30 General Supportive Care for the Laminitis Case 269Andrea E. Floyd and Debra R. Taylor31 Common Therapies: Anti-Inflammatory Therapy 277Thomas J. Divers32 Vasoactive Drug Therapy 284Simon R. Bailey and Susan C. Eades33 Analgesia 291Bernd Driessen and Laura Zarucco34 Digital Hypothermia 306Andrew W. van Eps and Christopher C. Pollitt35 Equine Sepsis 316Samuel D. Hurcombe and Susan J. Holcombe36 Equine Metabolic Syndrome 329Andy E. Durham37 Pituitary Pars Intermedia Dysfunction 334Dianne Mcfarlane, Philip J. Johnson and Harold C. Schott, IIPart 6: Treatment of Laminitis: Digital Support and Stabilization of the Distal Phalanx38 Therapeutic Shoes: Application of Principles 343Stephen E. O’Grady39 Solear Support Techniques 354Raul J. Bras40 Approaching Digital Management Prior to Displacement of the Distal Phalanx 360Randy B. Eggleston41 Hoof Care Management of Horses with Displacement of the Distal Phalanx 364Andrew H. ParksPart 7: Treatment of the Laminitis Case42 The Use of Casts in Equine Laminitis 377James K. Belknap and Raul J. Bras43 Deep Digital Flexor Tenotomy 382R. Wayne Waguespack, Jr44 Dorsal Hoof Wall Techniques 391Amy Rucker45 Complications of Laminitis 402Robert J. Hunt and James K. BelknapPart 8: Management of Chronic Laminitis46 Management Changes in the Laminitis Case 413Andrew Van Eps, Robert J. Hunt, James K. Belknap and Jeff RidleyPart 9: Prevention of Laminitis47 Overview of Laminitis Prevention 423James K. Belknap and Andy E. Durham48 Prevention of Supporting Limb Laminitis 427Harry J. Markwell and Gary M. Baxter49 Prevention of Sepsis-Related Laminitis 432Samuel D. Hurcombe and Susan J. Holcombe50 Nutritional Management for Avoidance of Pasture-Associated Laminitis 436Pat HarrisGlossary 442Index 445

"There is no comparable book in this field. As the first comprehensive book on equine laminitis, this will set the standard for years to come. Students, veterinary practitioners, and researchers will all find parts of it useful for their levels of expertise and experience...Anyone aspiring to equine practice will need to read and understand the various aspects of laminitis this book presents, or be forced to find the same information in widely-disparate sources. This book is, by far, the easiest method to comprehensively study this subject." (Doody Enterprises 31/03/2017)