Epigenetics and Assisted Reproduction

An Introductory Guide

Häftad, Engelska, 2018

Av Cristina Camprubí, Joan Blanco, Cristina Camprubi

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Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Produktinformation

Utgivningsdatum2018-08-24
Mått178 x 229 x 16 mm
Vikt400 g
FormatHäftad
SpråkEngelska
Antal sidor202
FörlagTaylor & Francis Ltd
ISBN9781138631632

Tillhör följande kategorier

Gynekologi och obstetrik inom Medicin
Reproduktionsmedicin inom Medicin

Cristina Camprubí is Founder and Director of GenIntegral, a genetic and epigenetic advisory service for professionals and patients. The author of more than twenty scientific papers published in high impact factor journals, and several book chapters, she participates as teacher/speaker in many postgraduate and specialist courses such as the Dexeus Forum Update in Obstetrics, Gynaecology and Reproductive Medicine.Joan Blanco is Professor at the Unitat de Biologia Cellular (Facultat de Biociències), Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain.

A Short Introduction to DNA Methylation. Epigenetic Modifications of Histones. Epigenetic Reprogramming in Early Embryo Development. Epigenetic Reprogramming of Mammalian Primordial Germ Cells. Laboratory Molecular Methodologies to Analyze DNA Methylation. Intrinsic and Extrinsic Factors That Influence Epigenetics. Epigenetic and Assisted Reproduction Epidemiological Studies. Epigenetics and Assisted Reproduction Experimental Studies: Sperm Epigenome. Epigenetic and Assisted Reproduction Experimental Studies: Sperm ncRNAs. Epigenetic and Assisted Reproduction Experimental Studies: Ovarian Stimulation. Epigenetic and Assisted Reproduction Experimental Studies: In Vitro Culture. Epigenetics: Hope against Genetic Determinism. Future Perspectives.