Ending Medical Reversal

Improving Outcomes, Saving Lives

Häftad, Engelska, 2019

AvVinayak K. Prasad,Adam S. Cifu,National Cancer Institute and National Institutes of Health) Prasad, Vinayak K. (Assistant Professor of Medicine,University of Chicago) Cifu, Adam S. (Professor of Medicine,K Prasad, Vinayak,S Cifu, Adam,Vinayak K Prasad,Adam S Cifu

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Why medicine adopts ineffective or harmful medical practices only to abandon them—sometimes too late.Medications such as Vioxx and procedures such as vertebroplasty for back pain are among the medical "advances" that turned out to be dangerous or useless. What Dr. Vinayak K. Prasad and Dr. Adam S. Cifu call medical reversal happens when doctors start using a medication, procedure, or diagnostic tool without a robust evidence base—and then stop using it when it is found not to help, or even to harm, patients.In Ending Medical Reversal, Drs. Prasad and Cifu narrate fascinating stories from every corner of medicine to explore why medical reversals occur, how they are harmful, and what can be done to avoid them. They explore the difference between medical innovations that improve care and those that only appear to be promising. They also outline a comprehensive plan to reform medical education, research funding and protocols, and the process for approving new drugs that will ensure that more of what gets done in doctors' offices and hospitals is truly effective.

Produktinformation

Utgivningsdatum2019-07-09
Mått150 x 226 x 23 mm
Vikt386 g
FormatHäftad
SpråkEngelska
Antal sidor280
FörlagJohns Hopkins University Press
ISBN9781421429045

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IntroductionPart IExamples, Frequency, and Consequences1. What Is Medical Reversal?2. Subjective OutcomesWhy Feeling Better Is Often Misleading3. Surrogate Outcomes4. Screening Tests5. Systems Failure6. Finding Flawed Therapies on Our Own7. The Frequency of Medical Reversal8. The Harms of Medical ReversalToday's Patients, Tomorrow's Patients, and the Health-Care FieldPart II9. A Primer on Evidence-Based MedicineWhat Is Evidence in Medicine?10. What Really Made You BetterWhen Evidence Gets ComplicatedPart III11. Scientific Progress, Revolution, and Medical Reversal12. Sources of Flawed Data13. Why Are We So Attracted to Flawed Therapies?Part IV14. Medical EducationA Very Good Place to Start15. Academic Medicine16. Reforming the SystemThe Burden of Proof and Nudging Our Way Past Reversal17. How Not to Become a Victim of Reversal18. Beyond DogmaWhen Randomized Trials Are UnnecessaryAcknowledgmentsAppendixReferencesIndex