Directed C-H Bond Functionalization

Streamlined, cost-effective, and environmentally benign concepts for the synthesis of chemical building blocks and pharmaceuticals Directed C-H Bond Functionalization summarizes recent advances in the field of selective and efficient C-H bond functionalization using directing groups. Written by a team of experts in the field, Directed C-H Bond Functionalization includes information on: History of the C-H bond activation and its discovery In-built functional group-directed C-H functionalization, proximal C-H bond functionalization, and template-assisted distal C-H bond functionalization Transient-directing group-assisted C-H bond functionalization and bifunctional non-covalent template-assisted C-H functionalization Redox catalytic methods and metal-free directed C-H functionalization reactions Industrial and synthetic application of directed C-H bond functionalization in organic synthesis, medicinal, and process chemistry With its all-encompassing approach, Directed C-H Bond Functionalization is a timely, essential reference for synthetic chemists in academia and industry working in the fields of organic synthesis, catalysis, sustainable chemistry, and drug design.