Crohn's Disease and Ulcerative Colitis

Daniel C. Baumgart, MDInflammatory Bowel Disease CenterDepartment of Gastroenterology and HepatologyCharité  Medical Center--Virchow HospitalMedical School of the Humboldt University of BerlinBerlin, Germany

• Foreword.- Preface.- Environmental Factors in the Epidemiology of Inflammatory Bowel Disease.- The Immune System in Health.- Understanding the Epithelial Barrier in IBD.- Intestinal Microbiology and Ecology in Crohn’s Disease and Ulcerative Colitis.- The Immune System in Inflammatory Bowel Disease: Antimicrobial Peptides.- Vascular Responses to Intestinal Inflammation.- Immunobiology of Human Dendritic Cells in Inflammatory Bowel Disease.- Immunobiology of T-cells in Inflammatory Bowel Disease.- Immunology of B-cells in Inflammatory Bowel Disease.- Immune Cells: Monocytes and Macrophages.- Immune Functions of Epithelial Cells in Inflammatory Bowel Disease.- Autophagy and Endoplasmic Reticulum Stress.- Matrix Metalloproteinases.- Paradigm of T-cell Differentiation in Irritable Bowel Disease.- Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal Inflammation.- Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel Disease.- Enhanced Endoscopy.- Magnetic Resonance Enterography.- Computed Tomography Enterography and Inflammatory Bowel Disease.- Ultrasound in Inflammatory Bowel Disease.- Laboratory Evaluation, Including Novel Diagnostic Markers.- Pathology of Inflammatory Bowel Disease.- Objective Assessment of Clinical Disease Activity.- Objective Assessment of Endoscopic Disease Activity and Mucosal Healing.- Evaluation of Quality of Life in Crohn’s Disease and Ulcerative Colitis: What Is Health-Related Quality of Life?.- Evaluation of Health Economics in Inflammatory Bowel Disease.- The Natural History of Inflammatory Bowel Disease.- Conventional Medical Management of Crohn’s Disease: Sulfasalazine.- Steroid Therapy for Crohn’s Disease.- Thiopurines in Crohn’s Disease.- Conventional Medical Management of Crohn’s Disease: Methotrexate.- Adalimumab for the Treatment of Crohn’s Disease.- Biologic Therapy of Crohn’s Disease: Certolizumab.- Biologic Therapy of Crohn’s Disease: Infliximab.- Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease Treatment.- Biologic Therapy of Crohn’s Disease: Natalizumab, Vedolizumab and anti-MadCAM.- Optimal Management of Fistulizing Crohn’s Disease.- Sulfasalazine and 5-aminosalicylates for Ulcerative Colitis.- Conventional Therapy of Ulcerative Colitis: Corticosteroids.- Medical Management of Ulcerative Colitis: Conventional Therapy—Azathioprine.- Calcineurin Inhibitors in Ulcerative Colitis.- Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: Infliximab.- Biologic Therapy of Ulcerative Colitis: Adalimumab.- Biologic Therapy of Ulcerative Colitis: Golimumab.- Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAM.- Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel Disease.- Biosimilars in the Treatment of Inflammatory Bowel Disease.- Step-up versus Top-down Approach in Crohn’s Disease.- Leukocytapheresis Therapy of Inflammatory Bowel Diease.- Surgical Management of Crohn’s Disease and Ulcerative Colitis.- Extraintestinal Manifestations: Autoimmune Hepatitis.- Primary Sclerosing Cholangitis.- Autoimmune Pancreatitis and Other Organ Involvement.- Cutaneous and Oral Manifestations of Inflammatory Bowel Disease.- Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel Disease.- Nutrition in Inflammatory Bowel Disease.- Pregnancy and Fertility in Inflammatory Bowel Disease.- Pediatric Aspects of Inflammatory Bowel Disease.- Management and Prevention of Infectious Diseases in Inflammatory Bowel Disease Patients.- Incidence of Cancer and Screening in Inflammatory Bowel Disease.- Inflammatory Bowel Diseases: How to Identify High Risk Patients.- Patient Perspective on Inflammatory Bowel Disease.- Patient Resources in Inflammatory Bowel Disease.

“This very complete book is an excellent resource on inflammatory bowel disease (IBD), discussing in detail all aspects of Crohn's disease and ulcerative colitis. … This book is written for a very broad audience, from physicians and scientists to all healthcare personnel, who deal with IBD patients. … All areas are covered in detail. Even though this is a large book, it is easy to read.” (Henrique Fernandez, Doody’s Book Reviews, September, 2017)