Coronary Heart Disease in Women

• 1 Epidemiology.- Definition.- The “MONItoring Cardiovascular Disease” Project of the WHO (WHO MONICA Project).- 2 Cardiovascular Risk Factors and the Development of Coronary Heart Disease in Women Smoking.- Smoking.- Dyslipidemia.- Lipoprotein (a).- Diabetes Mellitus.- Insulin Resistance and Polycystic Ovary Syndrome.- Family History of Coronary Heart Disease or Genetic Disposition.- Hypertension.- Sedentary Lifestyle.- Obesity.- Homocysteine.- High sensitivity C-reactive Protein.- Risk Factors Unique to Women.- 3 Pathophysiology of Coronary Heart Disease and the Effects of Estrogen.- Basics.- Effects of Estrogen.- 4 Stable Angina.- Definition and Pathophysiology of Angina Pectoris.- Diagnosis Based on Symptoms.- Diagnostic Evaluation.- Medical Management.- Percutaneous Coronary Intervention for Stable Angina.- 5 Acute Myocardial Infarction.- Progression from Stable Coronary Heart Disease to Myocardial Infarction.- Epidemiology of Acute Myocardial Infarction.- Pathophysiology.- Clinical Presentation of Acute Myocardial Infarction.- Criteria for the Diagnosis of Acute Myocardial Infarction.- Therapy.- Complications.- Prognosis.- Influence of Gender on the Referral for Coronary Angiography in Patients with Acute Myocardial Infarction.- 6 Acute Coronary Syndromes.- Non-ST-Elevation Myocardial Infarction/Unstable Angina.- Definition.- Presentation.- Diagnosis.- Therapy.- 7 Coronary Artery Bypass Surgery.- Operative Mortality.- Complications Associated with CABG.- Long-Term Outcomes.- Indication for CABG Surgery.- Comparison of CABG with Multivessel Angioplasty.- 8 Primary and Secondary Prevention of Coronary Heart Disease.- Class I Interventions.- Class II Interventions.- Class III Interventions.- 9 Hormone Replacement Therapy.- Hormone Replacement Therapy andPrevention of Coronary Heart Disease.- Observational Studies for Primary and Secondary Prevention.- Randomized Primary Prevention Trials.- Randomized Secondary Prevention Trials.- Clinical Implications of Hormone Replacement Therapy.- Biological Mechanisms of Hormone Replacement Therapy.- 10 Future Directions.

From the reviews: "This book gives a basic complete review of coronary artery disease (CAD) ... . it is useful for students, residents and primary care physicians. ... The best feature of the book is the concise, current and complete review of CAD management which makes it very useful for students and residents. The other nice feature is a complete review of the HRT trials and studies. Assessment: Overall, the book provides a good review of CAD management for men and women ... ." (Thriveni Sanagala, www.doody.com, February, 2004) "The text aims to cover broad areas related to coronary heart disease. ... The book is generally well set out and benefits from the summaries at the end of each chapter. There are several graphical illustrations that break up the text satisfactorily. Each chapter is well referenced, providing the opportunity to examine, the subject more comprehensively. In summary, this is an interesting book ... . It would appeal to cardiologists with a particular interest in gender-specific differences in ischaemic heart disease." (Interventional Cardiology Monitor, Vol. 10 (4), 2003) "The book is easy to read and studies all aspects of coronary heart disease ... . For each chapter, an overview of the actual knowledge is clearly presented and discussed with special emphasis on gender specificity. Keynotes are highlighted and a summarizing paragraph concludes each chapter. ... I would recommend the reading of this book to all cardiologists who are interested in an accurate synthesis of the most recent data about an emerging subject: coronary artery disease in women." (Agnes Pasquet, Acta Cardiologica, Vol. 59 (3), 2004)