“… question the positive and negative effects on the brain (and on health in general) of the consumption of three methylxanthine-containing substances: either coffee, tea and – to a lesser degree – chocolate. … will be an important addendum for basic and clinical scientists, since most results on these problems and issues can usually be found only in academic journals and not often in books. The other positive point here is the presence of a detailed index. Apart from doctors and chemists, I also believe that many nutritionists, neurologists and perhaps most coffee drinkers could enjoy most of that reading; in fact, although it is an academic publication with graphs and tables, one will find many elements in every chapter that can be understood without a specialization in chemistry or in neuropharmacology.” — Yves Laberge, Université Laval, Quebec, Canada, in the Journal of Chemical Neuroanatomy, Vol. 33, No. 3, February 2007