Chemical Biology

and Drug Discovery

Häftad, Engelska, 2022

1 009 kr

Beställningsvara. Skickas inom 10-15 vardagar

Fri frakt för medlemmar vid köp för minst 249 kr.

After an introduction to the problems addressed by chemical biology in drug discovery, the three levels of molecular biology dogma: DNA, RNA and proteins and their role as drug targets serve as the common thread of this book. This book is a translation of the original German 1st edition Chemische Biologie by Marco F.

Produktinformation

Utgivningsdatum2022-02-02
Mått168 x 240 x 16 mm
Vikt412 g
FormatHäftad
SpråkEngelska
Antal sidor223
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783662644119
OriginaltitelChemische Biologie

Tillhör följande kategorier

Kemi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Biokemi inom Naturvetenskap och teknik

Marco F. Schmidt is co-founder and Chief Scientific Officer of biotx.ai Inc. which develops Artificial Intelligence for biomedical data analysis. Together with his team, he researches how machine learning can be used to identify drug targets and predict the clinical effect of drug candidates. He studied biochemistry at the FU Berlin and in Tübingen, received his PhD in chemical biology at the FMP Berlin and worked on new drug concepts at the University of Cambridge.

Foreword.- Introduction.- Part I: Chemical Biology and Drug Development.- Chemical Biology - a Holistic Science.- Drug Development.- From Genomics to Chemical Biology.- Part II: DNA.- DNA - blueprint of proteins.- Genomic Variation.- Gene Therapy and Genome Editing.- Part III: RNA.- RNA - information and function carrier.- RNA Interference in Drug Development.- Part IV: Proteins.- Peptides & proteins.- Proteins as drug targets.- Chemical genomics - From target protein to drug.- From target protein to macromolecular drug - Biologics.- Chemical proteomics: From drug to target protein.- Chemical genetics: validation of drug target by elucidation of signaling pathway.- Chemical biology - Addressing new drug targets.