Cellular Adhesion in Development and Disease

Alpha Yap is a Professor and Head of the Division of Molecular Cell Biology at the Institute for Molecular Bioscience, The University of Queensland. After training in Internal Medicine, Endocrinology and Cell Physiology, he undertook post-doctoral research with Barry Gumbiner at Memorial Sloan-Kettering Cancer Center before returning to Australia to establish his independent research group. His laboratory studies the cellular mechanisms responsible for cadherin-dependent morphogenesis, notably the mechanisms and principles that coordinate cadherin adhesion with the cytoskeleton. He was Chair of the 2011 Gordon Research Conference on Cell Contact & Adhesion and will chair the 2016 GRC on Signaling by Adhesion Receptors. He currently serves on the editorial boards of several journals, amongst them Molecular Biology of the Cell, Developmental Cell and Current Biology. He is the recipient of the 2013 President’s Medal of the Australia and New Zealand Society for Cell and Developmental Biology.

• 1. How Adhesion forms the early Mammalian EmbryoMelanie D. White and Nicolas Plachta2. Regulation of Cell Adhesion and Cell Sorting at Embryonic BoundariesFrançois Fagotto3. Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional ContractilityRashmi Priya and Alpha S. Yap4. Integration of Cell-Cell Adhesion and Contractile Actomyosin Activity during MorphogenesisKatja Röper5. Nuclear Signaling from Cadherin Adhesion ComplexesPierre D. McCrea, Meghan T. Maher and Cara J. Gottardi6. Nectins and Nectin-Like Molecules in Development and DiseaseKenji Mandai, Yoshiyuki Rikitake, Masahiro Mori and Yoshimi Takai7. Anchors and Signals: The Diverse Roles of Integrins in DevelopmentAidan P. Maartens and Nicholas H. Brown8. Epithelial-Mesenchymal Transitions: From Cell Plasticity to Concept ElasticityPierre Savagner9. Embryonic Cell-Cell Adhesion: A Key Player in Collective Neural Crest MigrationElias H Barriga and Roberto Mayor10. VE-Cadherin in Vascular Development: A Coordinator of Cell Signaling and Tissue MorphogenesisAnne Karine Lagendijk and Benjamin M. Hogan11. Adhesion in Mammary Development: Novel Roles for E-Cadherin in Individual and Collective Cell MigrationEliah R. Shamir and Andrew J. Ewald12. Cell Adhesion in Epidermal Development and Barrier FormationKaelyn D. Sumigray and Terry Lechler13. Cadherin-Based Trans-Synaptic Networks in Establishing and Modifying Neural Connectivity Lauren G. Friedman, Deanna L. Benson and George W. Huntley14. Cell-Cell Interactions Driving Kidney MorphogenesisAlexander N. Combes, Jamie Davies and Melissa Little