Bone Toxicology

Susan Y. Smith is a consultant who specializes in nonclinical muscoloskeletal research. She provides guidance for the conduct of pharmacology, efficacy or safety studies, or help with data interpretation to unravel the mysteries of skeletal evaluations. She received a Master of Science in Pharmacology at McGill University and later joined Charles River Laboratories for almost 18 years and where she became Senior Scientific Director of Musculoskeletal Research. She has over 30 years of experience in preclinical safety assessments and toxicology and over 20 years of expertise in bone research.

• Bone Toxicology in Preclinical Drug Testing.- Bone Physiology and Biology.- Study designs and Regulatory Considerations.- Specific Considerations for Bone Evaluations for Pediatric Therapeutics.- Bone Pharmacology and other models in Preclinical Drug Testing.- Methods in Bone Toxicology.- Biochemical Markers and Hormones.- Imaging.- Biomechanics.- Pathology and Histomorphometry.- Integrated System Toxicology.- Bone and Muscle.- Bone and Reproductive System.- Bone and Kidneys.- Bone and Energy Metabolism.- Bone and Immune System.- Bone and Central Nervous System.- Bone and Other Organs.