Bioorganic Chemistry

• 1. Fundamentals of Nucleic Acids ; 2. Chemical Synthesis of DNA/RNA ; 3. Enzymatic Methods for Preparation and Manipulation of Nucleic Acids ; 4. Structure of DNA and RNAM. ; 5. Chemical Mapping of Nucleic Acid Conformation ; 6. Introduction to 1H NMR Spectroscopy of DNA ; 7. The Formation of Alternative Structures in DNA ; 8. Reporter Groups for the Analysis of Nucleic Acid Structure ; 9. Nucleic Acid Binding and Catalysis by Metal Ions ; 10. Small Molecule-DNA Interaction ; 11. The Chemistry of Protein-DNA Interactions ; 12. Antisense/Antigene Oligonucleotides ; 13. Catalytic RNA ; 14. The Polymerase Chain Reaction and In Vitro Random Selection

"It is an excellent starting point for any chemist seeking to familiarize him- or herself with current topics related to the chemistry, enzymology, molecular recognition, and structure of nucleic acids....This book succeeds in presenting a clear, yet suitabley advanced view of modern nucleic acid chemistry and thus will prove very useful to educators, students, and established researchers who are interested in this field." -- Journal of the AmericanChemical Society"...the editor and his contribuators have succeeded admirably in producing a modestly priced book that will be very useful, not only for its target audience of students but for anyone wishing to have a concise yet thorough overview of the field."--Manfred E. Wolff, Journal of Medicinal Chemistry