Biomarkers in Breast Cancer

Inbunden, Engelska, 2005

AvGiampietro Gasparini,Daniel F. Hayes,Daniel F Hayes

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Written by experts in the field, Biomarkers in Breast Cancer presents an updated view on the prognostic and predictive biomarkers in breast cancer covering the major advancements in the application of the novel sophisticated molecular methods as well as the conventional state-of-the art prognostic and predictive indicators. This text offers a critical view on the modern approach to the development of surrogate biomarkers of prognosis and responsiveness to selective treatments in breast cancer.

Produktinformation

Utgivningsdatum2005-10-01
Mått155 x 235 x 30 mm
Vikt862 g
FormatInbunden
SpråkEngelska
SerieCancer Drug Discovery and Development
Antal sidor342
Upplaga2006
FörlagHumana Press Inc.
ISBN9781588292278

Tillhör följande kategorier

Onkologi inom Medicin
Medicinsk utrustning och medicinska tekniker inom Medicin
Biokemi inom Naturvetenskap och teknik

General Topics.- Guidelines for the Design of Clinical Studies for the Development and Validation of Therapeutically Relevant Biomarkers and Biomarker-Based Classification Systems.- Analytical Aspects of Biomarker Immunoassays in Cancer Research.- Tissue Microarrays.- Assays for Gene Expression and Post-Translational Protein Abnormalities.- Gene Expression Profiling with DNA Microarrays.- Assays for DNA Abnormalities.- Assays for Gene Amplification.- Tissue Predictive Biomakers.- Cell Kinetics.- Urokinase-Type Plasminogen Activator and PAI-1.- Predictive Value of c--erb-B2 for Endocrine Therapy and Chemotherapy in Breast Cancer.- erb-B2 as a Therapeutic Target.- The Epidermal Growth Factor Receptor Pathway as a Selective Molecular-Targeted Treatment in Human Breast Cancer.- p53 as a Prognostic and Predictive Indicator.- Predictive Biomarkers in Body Fluids.- Occult Metastatic Cells in Breast Cancer Patients.- Circulating HER2/neu.- Circulating Vascular Endothelial Growth Factor.- Detection of Early Tumor Dissemination in Patients With Breast Cancer.- Future Directions.- New Technologies/New Markers/New Challenges.