Biology of Longevity and Aging

Pathways and Prospects

Inbunden, Engelska, 2019

AvRobert Arking,Wayne State University) Arking, Robert (Professor of Biological Sciences, Professor of Biological Sciences

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The latest edition of Robert Arking's seminal text on the biology of aging takes on an extended title, since the field of gerontology has advanced to a point at which it is possible to separate the topic into two implicit subsets, longevity and aging. This multi-faceted description of the biology of aging guides the reader through increasingly interesting answers to seven fundamental questions: What is aging? Why do we age? What mechanisms support extended longevity? What determines the onset of senescence? What is the mechanistic basis of senescence? Why do humans live so long? And lastly, what pro-longevity societal interventions are needed?Inevitably, humans will age but there is no reason why we must suffer from age-related diseases. Aging and longevity are dependent on both genes and social environment. Our biology does not forbid the modulation of aging. What we really want to know is not so much about the biology of aging - which is basically a degenerative process - but rather about biological processes underlying the long term maintenance of our health. New chapters incorporate the latest developments in the field of gerontology. Research done since the previous edition was published has given us insight into how we may stay healthier longer.

Produktinformation

Utgivningsdatum2019-02-07
Mått257 x 185 x 38 mm
Vikt1 451 g
FormatInbunden
SpråkEngelska
Antal sidor720
Upplaga4
FörlagOUP USA
ISBN9780199387960

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Robert Arking is Professor of Biological Sciences at Wayne State University. His research delves into the mechanisms underlying both senescence and extended longevity in Drosophila. He has published widely on these topics, and is a Fellow of both the Gerontology Society of America and the American Aging Association. He was a Fulbright Fellow at the University of Salzburg, Austria; and was twice invited to serve as an "Expert Visiting Professor" at Pusan University in South Korea.

Part I: What is Aging?Chapter 1. Perspectives on Aging.Chapter 2. Measuring Age-related Changes in PopulationsChapter 3. Measuring Age-related Changes in IndividualsPart 2: Why Do We Age?Chapter 4 Evolutionary & Comparative Aspects of Longevity and SenescencePart 3: What Mechanisms Modulate Our Longevity?Chapter 5 Interventions That Modify LongevityChapter 6 Genetic and Social Aspects Affecting Human LongevityChapter 7 Genetic Determinants of Longevity in Animal and Human ModelsPart 4: What Mechanisms Modulate Our Aging and Senescence?Chapter 8 What Mechanisms Underlie the Transition from Health to SenescenceChapter 9 Human Senescent PhenotypesChapter 10 Stochastic Mechanisms of SenescenceChapter 11 Systemic Mechanisms of SenescenceChapter 12 Senescence as a Breakdown of Intracellular Regulatory Processes.Chapter 13 Senescence as a Breakdown of Intercellular Regulatory ProcessesPart 5: An Integrated View of Longevity and Aging MechanismsChapter 14 Biological Theories of Senescence and the Evolution of Extended LongevityChapter 15 Aging -related Research and It's Impact on Society. ReferencesIndex