Biologically Active Substances of Protozoa

Häftad, Engelska, 2012

Av N.N. Sukhareva-Buell, N. N. Sukhareva-Buell

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The search for new producers of biologically active substances (BAS) against human and animal diseases continues to be an important task in biology and medicine. This book then is the result of the research on the project: "Biologically active substances of the Mastigophora (Flagellates)".

Produktinformation

Utgivningsdatum2012-10-08
Mått155 x 235 x 8 mm
Vikt207 g
FormatHäftad
SpråkEngelska
Antal sidor112
Upplaga2003
FörlagSpringer
ISBN9789401037877

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1. Protozoa as producers of biologically active substances.- 1.1 Trypanosoma cruzi as the source of medications; selection of other species among flagellates.- 1.2 Toxins and detoxification substances.- 1.3 Biologically active substances of soil Protozoa.- 2. Cultivation of flagellates.- 2.1 Media for cultivation of flagellates.- 2.2 Physiological role of main media components in the cultures of flagellates.- 2.3 Conditions for flagellates growth and stimulated biosynthesis of lipids.- 3. Lipids of flagellates.- 3.1 Phospholipids and sterols.- 3.2 Fatty acids and conditions for stimulated biosynthesis.- 3.3 Biosynthesis of lipids by flagellates.- 4. Glycosylated lipids of flagellates.- 4.1 Glycosyl-phosphatidylinositol (GPI) and related GIPL, LPG and LPPG.- 4.2 Biological functions of GPI and related glycophospholipids.- 5. Surface membrane glycoproteins of flagellates.- 5.1 Variant surface glycoproteins (VSGs) and their genes rearrangement.- 5.2 Sialic acids and trans-sialidases.- 5.3 Membrane mucins and mucin-like glycoproteins.- 6. Cytokines, eicosanoids and nitric oxide as effector molecules against parasitic flagellates.- 6.1 Cytokines.- 6.2 Eicosanoids.- 6.3 Nitric oxide.- 7. Biologically active substances of selected flagellates.- 7.1 Total lipid fraction: correlation between its composition and biological activity.- 7.2 Astasilid, its composition and biological activity.- 7.3 Membrane glycophospholipid (GPL) and it’s biological activity.- 7.4 Reserve polysaccharide from Astasia longa and it’s biological activity.- Conclusion.- References.