Biodegradable Long Acting Injectables and Implants

An Industry View

Inbunden, Engelska, 2025

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Long acting injectables and implants (LAI) are known to improve patient adherence and treatment outcomes. There is a trend toward increasing interest in the development of long-acting drugs for local administration versus systemic administration of depot products (i.e., IM or SC injection).

Produktinformation

Utgivningsdatum2025-03-30
Mått155 x 235 x 21 mm
Vikt569 g
FormatInbunden
SpråkEngelska
Antal sidor256
FörlagSpringer International Publishing AG
ISBN9783031723018

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Kemi inom Naturvetenskap och teknik
Tillverkningsteknik inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Farmakologi inom Medicin

Dr. Farshad Ramazani is a Senior Expert Science and Technology at Novartis Pharma AG in Basel, Switzerland, specializing in parenteral drug development. He has been instrumental in developing several patient-centric long-acting injectable formulations, now in various clinical trial phases. Dr. Ramazani regularly publishes research and review articles in leading pharmaceutical journals and is a co-inventor on three patents on long acting injectables. He received the TRD Culture Award in 2021 and 2023, and the Innovation Award of the Year in 2016 at Novartis. In 2010, he was among the top four candidates nationally to receive a PhD scholarship from the Iranian Health Ministry. He completed his PhD in 2015 at Utrecht University in the Netherlands, focusing on polymeric micro and nanoparticles for local and targeted drug delivery.

Preface.- Drug design for the development of long acting injectables.- Biodegradable polymers for development of LAI.- A roadmap for production of drug loaded poly (lactic-co-glycolic acid) (PLGA) microparticles: challenges and opportunities.- Biodegradable in situ forming and preformed implants.- Suspension-Based Long Acting Injectables.- Oil based solutions.- Clinical applications of LAI: systemic and local drug delivery.- Local Tolerability of Long-acting Injectables.- Envisaging the future.