Bacteriophage-Based Vectors in Gene Therapy

Inbunden, Engelska, 2026

AvRoderick Slavcev,Julia Lumini,Krish Devgan

2 419 kr

Kommande

Bacteriophages are powerful and versatile tools in genetic medicine. This book explores the innovative historical and current uses of these bacterial viruses to create targeted gene delivery systems, vaccines, and immunotherapeutics. It addresses the urgent need for cost-effective, scalable alternatives to traditional viral vectors by highlighting the transformative potential of phage-based platforms.The book is structured to provide a comprehensive framework for researchers and clinicians, exploring the biological and structural roles of different phage types. It also examines cutting-edge methodologies, including phage display technologies, genomic manipulations, chemical manipulations, hybrid vector development, and biomanufacturing innovations. Through case studies and comparative analyses, it reveals significant advances in vector functionality and therapeutic safety. This essential resource offers solutions to current vector limitations, helping to expand the potential of genetic medicine.

Produktinformation

Utgivningsdatum2026-07-01
Mått148 x 212 x undefined mm
FormatInbunden
SpråkEngelska
FörlagCambridge Scholars Publishing
ISBN9781036473044

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Roderick Slavcev is an Associate Professor with the University of Waterloo's School of Pharmacy, Canada. Dr Slavcev's research specializes in bacteriophage-based biotechnology and exploits phage genetic systems in the generation of novel therapeutic platforms.Julia Lumini is a Research Project Manager at the Slavcev Lab, focusing on advancing gene therapy and biomedical engineering. She holds a Bachelor's in Biomedical Science with dual focus on Biophysics and Medical Physiology and an MBA in Healthcare Management. Krish Devgan is an NSERC (Natural Sciences and Engineering Research Council) USRA (Undergraduate Student Research Award) student with the Slavcev Lab for Spring 2025, and is assisting with several different projects related to the iPhAGE System. He is in the 4th year of his BSc in Honours Health Science at McMaster University, Canada.Deborah Pushparajah is working as a research associate and scientist with the Slavcev Research Group. She completed her MSc in Pharmacy at the University of Waterloo in December 2022. Kate Nagge was a co-op research assistant with the Theraphage Lab, the University of Waterloo during Winter 2025. She was integral to the team, assisting with daily lab tasks and becoming adept at several experimental processes. She is currently pursuing Nursing at Conestoga College, Canada.