Advances in Nanotechnology for Ocular Drug Delivery: Innovations and Future Directions

This book presents a comprehensive exploration of the transformative potential of nanotechnology in overcoming longstanding challenges in ophthalmic drug delivery. This book brings together cutting-edge research and emerging innovations that aim to address the physiological and anatomical barriers impeding efficient drug transport to ocular tissues. Divided into thematic chapters, this book explores a wide range of nanocarrier systems, including polymeric nanoparticles, solid lipid nanoparticles, dendrimers, liposomes, niosomes, micelles, and inorganic nanomaterials, highlighting their design, mechanisms, and clinical potential. From enhancing ocular bioavailability to achieving sustained and targeted release, each chapter offers in-depth insights into the application of these technologies for treating anterior and posterior segment diseases such as glaucoma, macular degeneration, diabetic retinopathy, and dry eye syndrome. The book also explores next-generation strategies such as stimuli-responsive systems, gene delivery platforms, smart nanocarriers, and contact lens-based delivery, along with the regulatory and translational challenges that must be addressed for successful commercialization. It serves as an essential resource for pharmaceutical scientists, researchers, clinicians, and industry professionals seeking to develop patient-friendly, effective, and non-invasive ocular therapies. By combining foundational science with forward-looking perspectives, this book underscores the critical role of interdisciplinary innovation in revolutionizing ocular pharmacotherapy and shaping the future of nanomedicine in ophthalmology.