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If you had a complete copy of a dinosaur's DNA and the genetic code, you still would not be able to make a dinosaur,or even determine what one looked like. Why? How do animals get their shape and how does shape evolve? In this important book, Nobel laureate Gerald M. Edelman challenges the notion that an understanding of the genetic code and of cell differentiation is sufficient to answer these questions. Rather, he argues, a trio of related issues must also be investigated,the development of form, the evolution of form, and the morphological and functional bases of behaviour. Topobiology presents an introduction to molecular embryology and describes a comprehensive hypothesis to account for the evolution and development of animal form.
Gerald M. Edelman is director of the Neurosciences Institute and chairman of the Department of Neurobiology at the Scripps Research Institute. He received the Nobel Prize for Physiology or Medicine in 1972. He is also the author of Bright Air, Brilliant Fire Tobiology and The Remembered Present.
Form From Place * Animate Form * Code, Scale, and Place * Development * Pattern * Morphologic Evolution Molecular Mechanisms Of Epigenesis * Mechanochemistry and Cellular Driving Forces * Morphoregulatory Molecules The Morphoregulator Hypothesis: Mechanochemistry Linked To Developmental Genetics * The Developmental Genetic Question * The Evolutionary Question Development And Behavior * Developmental Variation and Somatic Selection: Neural Darwinism * Coda: The Other Side of Biology