The Fetal Matrix: Evolution, Development and Disease

Häftad, Engelska, 2004

1 179 kr

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New discoveries reveal how crucial interactions which determine our destiny occur before birth, when our genes interact with their environment as the embryo and fetus develop. These processes - in the matrix of the womb - are evolutionary echoes of mechanisms which allowed our hunter-gatherer ancestors to survive. These exciting insights into predictive adaptive responses suggest new ways of protecting the health of the fetus, infant and adult. If inappropriate they can trigger obesity, diabetes and heart disease, formerly thought to result solely from adult lifestyle. The new concepts in this book are crucial to understanding the daunting public health burden in societies undergoing rapid transition from poverty to affluence. They add an important new dimension to evolutionary theory. Synthesising developmental biology, evolutionary history, medical science, public health and social policy, this is a ground-breaking and fascinating account by two of the world's leading pioneers in this important emerging field.

Produktinformation

Utgivningsdatum2004-11-18
Mått175 x 247 x 13 mm
Vikt552 g
FormatHäftad
SpråkEngelska
Antal sidor272
FörlagCambridge University Press
ISBN9780521542357

Tillhör följande kategorier

Sjukdomar och rubbningar inom Medicin

1. Shaping our destiny: genes, environment and their interactions; 2. Mother and fetus; 3. Fetal choices; 4. Predictive adaptive responses and human diseases; 5. Obesity, diabetes and other diseases; 6. The biology of predictive adaptive responses; 7. Predictive adaptive responses - critical processes in evolution; 8. Evolutionary echoes and the human camel; 9. Improving human health; 10. Fetal futures.

'Gluckman and Hanson argue that the interaction between mammals and their environment while in the womb irreversibly affects their future development, what they call a 'predictive adaptive response'. It also has huge health implications for the rest of their lives. The authors are persuasive, and their findings have relevance for health policy everywhere. If maternal well-being affects the lifelong health of the offspring, it makes good sense to ensure that mothers are always well cared for.' New Scientist

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