This sociological consideration of illness and disease in contemporary America comes from a professor (Boston Coll.) who uses his own suffering, treatment, and theory along with reports of 50 others who volunteered to talk with him about their major depressive episodes. Karp writes well, addressing psychological, chemical, and cultural perspectives, with much credit to C. Wright Mills, Erving Goffman, and Arthur Kleinman. Many psychiatrists would agree that too little attention is paid to the nature of the pain and the impact of social context on our definitions of normality and treatment. "Self-help" comes under fire, too, as shallow ideology in a time of advancing anomie. A careful, honest writer, Karp has produced a classic equal to William Styron's Darkness Visible (LJ 8/90) and Clifford Beers's A Mind That Found Itself (1908). Highly recommended for sufferers, would-be healers, and anyone interested in the effects of depression. E. James Lieberman, Library Journal