Del 623 - Methods in Enzymology

RNA Recognition

Inbunden, Engelska, 2019

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RNA Recognition, Volume 623, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume covers a variety of topics, including The Preparation of cooperative RNA recognition complexes for crystallographic structural studies, Methods for thermal denaturation studies of fluorogenic aptamers, Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery, Using a click chemistry assay to identify natural product ligands for pre-microRNAs, Lessons from exploration of chemical and structural small molecule:RNA space, Using ligand-observed NMR to study RNA-small molecule interactions, and much more.

Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in the Methods in Enzymology series
Includes the latest information on RNA Recognition

Produktinformation

Utgivningsdatum2019-06-25
Mått152 x 229 x 36 mm
Vikt810 g
FormatInbunden
SpråkEngelska
SerieMethods in Enzymology
Antal sidor468
FörlagElsevier Science
MedarbetareHargrove,AmandaE.
ISBN9780128168318

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

1. Preparation of cooperative RNA recognition complexes for crystallographic structural studiesChen Qiu, Aaron C. Goldstrohm and Traci M. Tanaka Hall2. Methods for thermal denaturation studies of nucleic acids in complex with fluorogenic dyesLauren M. Aufdembrink, Tanner G. Hoog, Matthew R. Pawlak, Benjamin F. Bachan, Joseph M. Heili and Aaron E. Engelhart3. Identifying and validating small molecules interacting with RNA (SMIRNAs)Matthew D. Disney, Sai Pradeep Velagapudi, Yue Li, Matthew G. Costales and Jessica L. Childs-Disney4. Dynamic combinatorial chemistry as a rapid method for discovering sequence-selective RNA-binding compoundsJohn D. McAnany and Benjamin L. Miller5. A click chemistry assay to identify natural product ligands for pre-microRNAsAmanda L. Garner, Daniel A. Lorenz and Erin E. Gallagher6. Differentiation and classification of RNA motifs using small molecule-based pattern recognitionGiacomo Padroni, Christopher S. Eubanks and Amanda E. Hargrove7. Ligand-observed NMR techniques to probe RNA-small molecule interactionsDavid R. Calabrese, Colleen M. Connelly and John S. Schneekloth Jr.8. Synthetic bPNAs as allosteric triggers of hammerhead ribozyme catalysisYufeng Liang, Jie Mao and Dennis Bong9. Using Rosetta for RNA homology modelingAndrew Watkins, Ramya Rangan and Rhiju Das10. Monitoring co-transcriptional folding of riboswitches through helicase unwindingChristopher P. Jones, Subrata Panja, Sarah A. Woodson and Adrian R. Ferré-D’Amaré11. Strategies for understanding RNA recognition by X-ray and NMR methodsAiai Sun, Kaiyi Huang, Luqian Zheng and Aiming Ren12. Sensitive detection of structural features and rearrangements in long, structured RNA moleculesRebecca L. Adams, Nicholas C. Huston, Rafael C.A. Tavares and Anna M. Pyle13. A fluorescent aminosugar to rapidly screen and study RNA bindersNihar Ranjan and Dev P. Arya14. The use of electrospray ionization mass spectrometry to monitor RNA-ligand interactionsDanielle N. Dremann and Christine S. Chow15. Design of RNA-targeting macrocyclic peptidesMatthew J. Walker and Gabriele Varani16. Molecular recognition of HIV-1 RNAs with branched peptidesAshley N. Peralta, Yumin Dai, Chringma Sherpa, Stuart F.J. Le Grice and Webster L. Santos17. Sequence-specific recognition of structured RNA by triplex-forming peptide nucleic acidsDziyana Hnedzko and Eriks Rozners18. Evaluating riboswitch optimalityHannah Wayment-Steele, Michelle Wu, Michael Gotrik and Rhiju Das