This volume features a discussion of recent advances related to the cellular and molecular mechanisms mediating the generation of reactive oxygen and nitrogen species and their role in the pathogenesis of human disease, with a particular focus on the respiratory and cardiovascular systems. The volume brings together contributions from basic and clinical scientists in the field with unique approaches and research efforts. The information presented may help facilitate future collaborative studies that will lead to new insights into the pathogenesis of cardiopulmonary diseases characterized by excessive oxidative and nitrosative stress and may suggest innovative directions for therapeutic intervention.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member
Debra L. Laskin is the author of Oxidative / Nitrosative Stress and Disease, Volume 1203, published by Wiley.
Role of oxidative/nitrosative stress-mediated Bcl-2 regulation in apoptosis and malignant transformation Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft modelThe role of iNOS-mediated DNA damage in infection- and asbestos-induced carcinogenesisRegulation of apoptosis through cysteine oxidation : implications for fibrotic lung diseaseInhibition of inflammation and carcinogenesis in the lung and colon by tocopherolsReactive oxygen species and [alpha, beta]-unsaturated aldehydes as second messengers in signal transductionRedox signaling in inflammation : interactions of endogenous electrophiles and mitochondria in cardiovascular diseaseOxidative stress : acute and progressive lung injuryMacrophages, reactive nitrogen species, and lung injuryCigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction : role of VEGFR2Nitric oxide and zinc homeostasis in pulmonary endotheliumInhibition of epithelial sodium channels by respiratory syncytial virus in vitro and in vivoMolecular mechanisms of oxidative stress in airways and lungs with reference to asthma and chronic obstructive pulmonary diseaseOxidants and antioxidants in sulfur mustard-induced injury. Potential mechanisms for reduced delivery of nitric oxide to peripheral tissues in diabetes mellitusAcute effects of motor vehicle traffic-related air pollution exposures on measures of oxidative stress in human airways Genetic mechanisms of susceptibility to ozone-induced lung diseaseMechanisms of oxidant generation by catalaseRedox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiologyThe role of oxidative stress in the pathogenesis and treatment of asthmaOxidative/nitrosative stresses trigger type I diabetes : preventable in streptozotocin rats and detectable in human diseaseDetection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients : relation to clinical and laboratory measures of inflammationVascular oxidative stress and inflammation increase with age : ameliorating effects of [alpha]-lipoic acid supplementationMeasurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach