Management of Chronic Kidney Disease and Its Complications

Häftad, Engelska, 2027

AvThakur Gurjeet Singh,Rajwinder Kaur,Rupinder Kaur,Sumitha Elayaperumal,Nitin Gupta

2 479 kr

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Management of Chronic Kidney Disease and Its Complications? presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.

The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.

Management of Chronic Kidney Disease and Its Complications?is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

Explores the molecular, genetic, and epigenetic mechanisms underlying CKD and its diverse complications, providing a comprehensive understanding of disease pathophysiology
Examines the diagnosis and management of cardiovascular, metabolic, neurological, hematological, and urologic complications associated with CKD to support holistic patient care
Discusses emerging therapeutic approaches including precision medicine, regenerative therapies, gut microbiota modulation, and the application of artificial intelligence and machine learning in early detection and treatment
Addresses the unique challenges and management strategies for special populations such as pediatric, geriatric, and pregnant patients with CKD
Integrates evidence-based pharmacological, nutritional, and lifestyle interventions alongside psychosocial considerations to optimize clinical outcomes and quality of life for CKD patients

Produktinformation

Utgivningsdatum2027-02-01
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor645
FörlagElsevier Science
ISBN9780443444111

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Biologi inom Naturvetenskap och teknik

Dr. Thakur Gurjeet Singh is a pharmacology researcher with extensive graduate training in clinical and preclinical drug development. His work focuses on the neuroprotective mechanisms of pharmacological preconditioning in neurodegenerative disorders such as Alzheimer’s disease, Parkinsonism, stroke, epilepsy, and dementia. He has investigated key protective pathways involving adenosine, opioids, CGRP, calcium signaling, protein kinase-C, heat shock proteins, and MAP kinase. His research also explores novel therapeutic pathways using agents such as morphine and capsaicin, with additional expertise in mechanistic studies of substance dependence, including nicotine, alcohol, and morphine addiction. Dr. Singh’s core competencies include animal model development and validation, anesthetic and preconditioning techniques, histopathological analysis, and behavioral data evaluation. His broader interests include ALS, stem cell therapy, and movement disorders such as tardive dyskinesia.Prof. (Dr.) Rajwinder Kaur is the Assistant Dean of Pharm D (Academics) at Chitkara College of Pharmacy, Chitkara University, Punjab, India. With sixteen years of experience in teaching and research, she has held positions such as DST Women Scientist (WOS-A) at Punjab University, Chandigarh, and received prestigious fellowships like the CSIR-SRF and UGC-MRP. Dr. Kaur was awarded the "Dr. Harpal Singh Buttar and Harinder Kaur Buttar Young Scientist Award in Pharmaceutical Sciences for Rural Women" in 2013 and the Young Scientist Award "Women in Pharmaceutical Sciences" in 2023. Her research focuses on computational drug design, synthesis of fused-heterocyclic compounds, nanomedicine, and AI, particularly in inflammation, asthma, and neurological disorders. Dr. Kaur has published over 50 papers and 10 book chapters, and has edited a book. She is a senior member of the Hong Kong Chemical, Biological & Environmental Engineering Society (HKCBEES) and a life member of the Indian Pharmacy Graduate Association (IPGA). Dr. Rupinder Kaur is Assistant Professor at Chitkara College of Pharmacy, Chitkara University, Punjab, India. Her research interests revolve around management and advancement of pharmacotherapeutic approaches towards kidney diseases. Dr. Sumitha Elayaperumal is Assistant Professor at the JSS Academy of Higher Education and Research, Mysore, Karnataka. Her specialization is on molecular diagnosis of Coagulation platelet, thrombotic, and oncology disorders. Dr. Nitin Gupta is Director for Neelam Hospital, Rajpura, Punjab. Dr. Gupta is a leading urologist, laparoscopy, and renal transplant surgeon with a strong interest in advanced laparoscopic procedures. He has performed over 5000 endourological procedures, including more than 1200 PCNLs and over 1500 advanced laparoscopic surgeries such as laparoscopic donor nephrectomy, pyeloplasty, and nephrectomy.

1. Introduction to Chronic Kidney Disease (CKD)2. Genetic Contributions to the Development of Kidney Disease3. Diagnostic Evaluation of CKD4. Molecular Basis of CKD (Pathways, role of inflammation and oxidative stress)5. Complications of CKD6. Cardiovascular complications and its management (Vascular calcification)7. Vascular Diseases (Renovascular Disease; Thrombotic Microangiopathies)8. Hematological complications and its management9. Metabolic complications and its management (CKD-MBD)10. Gastric complications and its management11. Neurological complications (eg; Dystonia)12. Hypertension in CKD: Pathogenesis and Management13. Diabetic Nephropathy: Pathophysiology and Management/Treatment Strategies14. Glomerular Diseases15. Tubulointerstitial Diseases16. Risk of Infections in CKD (Urinary Tract Infections; Sepsis Management)17. Management strategies in CKD (Pharmacological Interventions and Lifestyle modifications)18. Nutritional Management in CKD (Dietary Restrictions and Nutritional Supplements)19. CKD in Pediatric population (Special Considerations and Challenges)20. CKD in Geriatric population (Treatment Considerations and Challenges)21. CKD in Pregnancy22. Psychosocial Aspects of Chronic Kidney Disease: Addressing Mental Health and Quality of Life23. Advances in Understanding and Treating Cystic Kidneys24. Renal Replacement Therapy25. Herbal approaches in the management of CKD26. Emerging Research and Therapies /interventions27. Epigenetics and CKD28. Precision Medicine in CKD-Genetic and Epigenetic Insights29. Gut Microbiota and CKD- A New Therapeutic Target30. Regenerative Medicine in CKD:-Stem Cells and Tissue Engineering31. Artificial Intelligence and Machine Learning in Early CKD Detection and Management32. Kidney Disease Secondary to Urologic Conditions: Stones, Calcinosis, Obstruction, and More