Magnesium and Its Alloys as Implant Materials

Corrosion, Mechanical and Biological Performances

Häftad, Engelska, 2023

AvMirco Peron,Filippo Berto,Jan Torgersen

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Despite their tremendous potential, Mg and its alloys are not yet used in biomedical applications. This book aims to provide scientific insights into the challenges of the materials, and give an overview of the research regarding their mechanical properties, corrosion behaviour and biological performances. The authors intend to put the reader into the position to accurate discern the proper Mg-based material for his/her applications and to choose the proper improvement strategy to his/her cause. To this aim, the manuscript is structured as follow: in Section 2, the main challenges hampering the use of magnesium in biomedical applications and the common improvement strategies are listed. In Section 3, the most investigated Mg alloys are reported in separate sub-sections, detailing their mechanical properties, corrosion behaviour and biotoxicity. High-pure and ultra-high-pure Mg, Al-based Mg alloys, Zn-based Mg alloys, Ca-based alloys and RE-based Mg alloys have been considered. In Section 4, the alloys’ performances with respect to the challenges is summarized providing the reader with useful information and suggestions on the potentially most suited choice. Finally, in Section 5, an outlook portraying the authors’ opinion of the future development of the field will be provided. This book will allow biomedical engineers, surface scientists, material scientists, implant manufacturers and companies working on implant approval an overview of the state-of-the-art technologies adopted so far to overcome the drawbacks of Mg for biomedical applications. Particular emphasis is put on explaining the link between mechanical, corrosion and biocompatible properties of Mg and its alloys as well as their pros and cons. In doing so, the authors intend to put the reader into the position to accurate discern the proper Mg-based material for his/her applications and to choose the proper improvement strategy to his/her cause.

Produktinformation

Utgivningsdatum2023-10-02
Mått156 x 234 x undefined mm
Vikt320 g
FormatHäftad
SpråkEngelska
Antal sidor194
FörlagTaylor & Francis Ltd
ISBN9781032654331

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Mirco Peron earned his degree in mechanical engineering (summa cum laude)in 2015 from the University of Padova, where his thesis evaluated the fatiguedamage and stiffness evolution in composite laminates. He is currently a PhDstudent at Norwegian University of Science and Technology (NTNU), Trondheim.His PhD topic deals with the optimization of mechanical and corrosionproperties of magnesium and its alloys for biomedical applications, with particularreference to the corrosion-assisted cracking phenomena.Filippo Berto is Chair of Structural Integrity at the Norwegian University ofScience and Technology in Norway. He is in charge of the Mechanical andMaterial Characterization Lab in the Department of Mechanical and IndustrialEngineering. He is author of more than 500 technical papers, mainlyoriented to materials science engineering, the brittle failure of different materials,notch effect, the application of the finite element method to the structuralanalysis, the mechanical behavior of metallic materials, the fatigue performanceof notched components as well as the reliability of welded, bolted andbonded joints. Since 2003, he has been working on different aspects of thestructural integrity discipline, by mainly focusing attention on problemsrelated to the static and fatigue assessment of engineering materials with particularattention to biomedical and medical applications and materials.Jan Torgersen is Professor of mechanical engineering at NTNU, Trondheim.He received his PhD from Vienna University of Technology, where he workedon high-resolution laser microfabrication of hydrogels for tissue engineering.He was pioneering in the work of processing hydrogel formulations at micronscale resolution in vivo, in the presence of living cells and whole organisms.He received a postdoctoral fellowship to work on a nanoscale vapor depositiontechnique called atomic layer deposition, allowing conformal coating ofthermally fragile and nanostructured substrates with atomically thin layers ofa wide range of materials. He contributed to the development of a selflimitingdeposition process for high-k materials for Dynamic Random AccessMemory (DRAM) applications. His current research interests are micro- andnanofabrication as well as surface functionalization, with particular focus onbiomedical applications.

Chapter 1 Introduction Introduction ReferencesChapter 2 Challenges and Common Strategies Introduction Corrosion Mitigation Strategies Impurities Removal Alloying Grain Size Modiﬁcation Mechanical Properties Tuning Grain Reﬁnement Solid Solution Strengthening Precipitation Hardening Interplay among Mechanical Properties, Corrosion Resistance and BiocompatibilityReferencesChapter 3 Synopsis of Properties of Biocompatible Mg and Its Alloys Introduction High-Pure Magnesium High-Pure Magnesium: Mechanical Properties High-Pure Magnesium: Corrosion Resistance High-Pure Magnesium: Biocompatibility Aluminum-Based Alloys AZ Alloys AZ Alloys: Mechanical Properties AZ Alloys: Corrosion Resistance AZ Alloys: Biocompatibility AM Alloys AM Alloys: Mechanical Properties AM Alloys: Corrosion Resistance AM Alloys: Biocompatibility Mg–Al–RE Alloys Mg–Al–RE Alloys: Mechanical Properties Mg–Al–RE Alloys: CorrosionResistance Mg–Al–RE Alloys: Biocompatibility Mg–Zn Alloys Mg–Zn Binary Alloys Mg–Zn Binary Alloys: Mechanical Properties Mg–Zn Binary Alloys: CorrosionResistance Mg–Zn Binary Alloys: Biocompatibility Mg–Zn–Zr Alloys Mg–Zn–Zr Alloys: Mechanical Properties Mg–Zn–Zr Alloys: CorrosionResistance Mg–Zn–Zr Alloys: Biocompatibility Mg–Zn–Ca Alloys Mg–Zn–Ca Alloys: Mechanical Properties Mg–Zn–Ca Alloys: CorrosionResistance Mg–Zn–Ca Alloys: Biocompatibility Mg–Zn–Ca BMGs Mg–Zn–Ca BMGs: Mechanical Properties Mg–Zn–Ca BMGs: Corrosion Resistance Mg–Zn–Ca BMGs: Biocompatibility Mg–Zn–Mn Alloys Mg–Zn–Mn Alloys: Mechanical Properties Mg–Zn–Mn Alloys: CorrosionResistance Mg–Zn–Mn Alloys: Biocompatibility Mg–Zn–RE Alloys Mg–Zn–RE Alloys: Mechanical Properties Mg–Zn–RE Alloys: CorrosionResistance Mg–Zn–RE Alloys: Biocompatibility Mg–Ca Alloys Mg–Ca Alloys: Mechanical Properties Mg–Ca Alloys: Corrosion Resistance Mg–Ca Alloys: Biocompatibility Mg–RE Alloys Mg–RE Alloys: Mechanical Properties Mg–RE Alloys: Corrosion Resistance Mg–RE Alloys: Biocompatibility ReferencesChapter 4 Tackling the Challenges Introduction Radar Chart: An Easy Tool to Compare Corrosion, Mechanical and Biological Performances ReferencesChapter 5 OutlookReferenceAppendix A: CorrosionAppendix B: In Vitro Biocompatibility AssessmentIndex