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This timely new volume in the highly acclaimed Neuromethods series focuses on major new advances in understanding the signaling mechanisms employed by neural tissues. Chapters, contributed by experts in the field, provide thorough, up-to-date coverage of a variety of topics and techniques, including: single-cell imaging technology phosphorylation of target proteins analysis of phosphoinositides and inositol phosphates inositol trisphosphate and intracellular calcium guanine nucleotide-binding proteins ion channel gating measurement of intracellular calcium with fluorescent calcium indicators protein kinase C synthetic analogs of intracellular messengers cyclic nucleotides caged intracellular messengers intracellular regulators and components of the exocytotic pathway intracellular messengers in vertebrate and invertebrate photoreceptors. Neuromethods 20 Intracellular Messengers is an essential resource for neurobiologiests at all levels of research.
Identification and Analysis of Function of Heterotrimeric Guanine Nucleotide-Binding Proteins Expressed in Neural Tissue.- Methods for the Analysis of Phosphoinositides and Inositol Phosphates.- Inositol Triphosphate Receptors and Intracellular Calcium.- Measurement of Intracellular Calcium with Fluorescent Calcium Indicators.- Single-Cell Imaging Technology.- Analysis of Protein Kinase C Function.- Synthetic Analogs of Intracellular Messengers.- Methods in Cyclic Nucleotide Research.- Caged Intracellular Messengers and the Inositol Phosphate Signaling Pathway.- Protein Phosphorylation.- Investigation of the Intracellular Regulators and Components of the Exocytotic Pathway.- Intracellular Messengers in Vertebrate Photoreceptors.- Intracellular Messengers in Invertebrate Photoreceptors Studied in Mutant Flies.
An extensive review of current knowledge of intracellular information processing...comprehensive...[Offers] a valuable extension to 'classical' neurobiology and provides new tools in neurochemistry.-Journal of Chemical Neuroanatomy