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A vast number of biochemical reactions are catalysed by molecules fixed to the surface of membranes (or other biological structures) with molecules in the surrounding solution. The study of the mechanisms at these "Biointerfaces" are becoming increasingly important for the understanding of biological catalysts, such as enzymes. This project is the first book to deal with the physical and chemical principles of an emerging field of science, for which the authors have set the ground-work.* The first book to deal with this newly emerging area. * Concentrates on the chemical and physical foundation of enzyme catalysis * Key area for the deeper understanding of biocatalytic processes * Examples for proteins and nucleic acids, two central areas of biochemical and bioorganic research
Otto G. Berg and Mahendra Kumar Jain are the authors of Interfacial Enzyme Kinetics, published by Wiley.
PrefaceTheory BoxesList of SymbolsWhy Interfacial Enzymes?Interface Phenomena: Accessibility and ExchangeTo Be or Not To Be: Dilemma for the Substrate in SolutionInterfacial Processivity: Ensemble Behavior in the Scooting ModeAnalysis of the Processive Reaction ProgressDetailed Balance Conditions for Interfacial EquilibriaRapid Substrate Replenishment in the Quasi-Scooting ModeInterfacial AllosteryInhibition: Specific or NonspecificThe Delay to the Steady State in the Reaction ProgressNonidealities of the Dispersed PhasesEffects of Reduction of Dimensionality
"...outlines the principles, rules, and analytic protocols for the kinetic analysis of the catalytic functions of enzymes at interfaces." (SciTech Book News, Vol. 26, No. 2, June 2002)