Hedgehog Signaling Protocols

In both vertebrates and invertebrates, Hedgehog signaling regulates the development of the tissues and structures of the body. In addition, many cancers and diseases arise as a result of misregulation of thepathway, which makesit an incredibly important system to understand. This volumeexamines various methods used in the analysis of the Hedgehog signaling pathway, bringing together different lines of analyses into one accessibleand comprehensive text.Thisvolume provides a single sourcefor investigators, presentingseveral different experimentalapproaches, which are all varied and broad in nature, as well as procedures for avariety of different model systems. Researchers will find this volume to be an invaluble tool as they work towards deeper understanding of the underlying molecular events that the Hedgehog signaling pathway regulates.