Handbook of Incretin-based Therapies in Type 2 Diabetes

Stephen Gough is Professor of Diabetes at the University ofOxford and Consultant Physician at the Oxford University Hospitals NHS Trust.Professor Gough graduated in medicine from Leeds University Medical School,where he was later awarded a higher degree Doctorate in Medicine, which focusedon cardiac dysfunction and abnormalities in coagulation and fibrinolysispresent at the time of diagnosis of type 2 diabetes. He is currently based atthe Oxford Centre for Diabetes, Endocrinology and Metabolism, where he is apracticing clinician in diabetes. His research interests and ongoing researchstudies include translational aspects of diabetes, with a focus on thephysiology of islet cell and whole organ pancreas transplantation, incretinbiology, and incretin therapies in diabetes. Professor Gough has previously hada strong interest in the genetic susceptibility to autoimmunity and this workhas been extended into his work on pancreas transplantation. He has publishedhis research extensively in peer-reviewed journals and has contributed to manynational and international conferences and books on diabetes. In recent years,Professor Gough has helped develop translation research in diabetes in Oxfordthrough a number of local and national initiatives, including the OxfordBiomedical Research Centre, and he is Clinical Lead in Diabetes for the OxfordAcademic Health Science Network and the Oxford Local Clinical Research Network.AddendumSince editing this book, Professor Gough has taken up theposition of Senior Principal Clinical Scientist with Novo Nordisk. He continuesas Visiting Professor of Diabetes at the University of Oxford and HonoraryConsultant with the Oxford University Hospitals NHS Trust.

• Introduction and disease overview.- Incretin hormones as a target for therapy.- Glucagon-like peptide receptor agonists.- Dipeptidyl peptidase-4 inhibitors.- Global position and recommendations for use.- Future and emerging therapies.