This handbook consists of 23 chapters from entrepreneurship, business, tourism, management, and other researchers from around the world, who discuss key issues and aspects of planning and operating business ventures in tourism from a managerial and marketing perspective. It covers the whole process of developing and managing the entrepreneurial process, from the conception of the entrepreneurial idea to the development and implementation of its business plan. It addresses tourism and its characteristics and the importance of entrepreneurship and entrepreneurs; key issues of the business environment in tourism, including strategic analysis and competition analysis and innovation and creativity; issues of planning the business project, including legal issues, feasibility analysis, and collaborative forms and strategies; issues of managing the business operation, such as financial matters, service quality and customer care, evaluating business performance, and risk management; tools and processes of marketing the business offering and services; and special topics like crowdsourcing, social entrepreneurship, green entrepreneurship, the sharing economy, and the contribution of creative tourism to entrepreneurship.