Transplantation of the Liver

Dr. Ronald W. Busuttil is Distinguished Professor and Executive Chairman of the UCLA Department of Surgery and holds the William P. Longmire, Jr. Chair in Surgery. He is the founding Chief of the Division of Liver and Pancreas Transplantation and Director of the Pfleger Liver Institute. In 1984, he founded the Liver Transplant Program at UCLA and has been the Director and Chief Surgeon for 28 years. Dr. Busuttil has authored more than 600 peer reviewed scientific manuscripts, 55 book chapters, and 400 abstracts. He is a Past President of the International Liver Transplantation Society, a Past President of the American Society of Transplant Surgeons, Past First Vice President of the American Surgical Association, a past member of the council of The Transplantation Society, and has served on the Board of Directors of United Network for Organ Sharing. Dr. Goran Klintmalm is chairman and chief of the Annette C. and Harold C. Simmons Transplant Institute at Baylor University Medical Center in Dallas, Texas, and past President of the American Society of Transplant Surgeons (ASTS). Dr. Klintmalm began the first multi-organ transplant program at Baylor in 1984. The program has now performed over 4,300 liver transplants and over 4,600 kidney transplants to date. In 1999, he performed the first split liver transplant in North Texas and the first adult living donor transplant in Texas in 2001. Dr. Klintmalm is the author of more than 450 peer-reviewed and over 80 non-peer-reviewed publications, editor of 45 textbooks chapters and 250 published abstracts. He is the Editor of 5 textbooks and has served as editor/associate editor/reviewer for multiple journals. established and has maintained the Baylor Biorepository and prospective Clinical Research Database in liver transplantation since 1985.

• I: General Considerations1. History of Liver Transplantation2. Surgical Anatomy of the Liver3. Molecular and Cellular Basics of Liver Failure4. Influence of Transplantation on Liver Surgery5. Organ Allocation: The US Model 6. Organ Allocation: The European Models 7. Donation After Cardiac or Brain Death: Regulatory and Ethical PrinciplesII: Patient Evaluation: Adult8. Current Indications, Contraindications, Delisting Criteria, and Timing for Transplantation9. Transplantation for Hepatitis A and B10. Natural History of Hepatitis C11. Transplantation for Hepatitis C12. Transplantation for Fulminant Hepatic Failure13. Transplantation for Primary Biliary Cirrhosis14. Transplantation for Sclerosing Cholangitis15. Transplantation for Autoimmune Hepatitis16. Transplantation for Primary Hepatic Malignancy17. Transplantation for Cholangiocarcinoma18. Transplantation for Metastases19. Transplantation for Hematological Disorders20. Transplantation for Budd-Chiari Syndrome21. Transplantation for Alcoholic Liver Disease22. Transplantation for Nonalcoholic Steatohepatitis23. Unusual Indications for TransplantationIII: Patient Evaluation: Pediatric24. General Criteria for Transplantation in Children25. Transplantation for Cholestatic Liver Disease in Children26. Transplantation for Biliary Atresia in Children 27. Transplantation for Metabolic Disease in Children28. Transplantation for Hepatic Malignancy in ChildrenIV: Special Considerations in Patient Evaluation 29. Ethical Decisions in Transplantation30. Psychiatric Assessment of Liver Transplant Candidates 31. Pretransplantation Evaluation: Cardiac32. Pretransplantation Evaluation: Renal33. Pretransplantation Evaluation: Infectious Disease34. Role of the Clinical Nurse Coordinator35. Radiological Evaluation in Transplantation36. Monitoring and Care37. Nutritional Aspects of Transplantation in Adults38. Management of Portal Hypertensive Hemorrhage39. Portopulmonary Hypertension and Hepatopulmonary Syndrome V: Operation 40. Donor Selection and Management41. Extended Criteria Donors42. Donating After Cardiac Death43. The Donor Operation44. Principles of Liver Preservation45. Recipient Hepatectomy and Grafting46. Anesthesia for Liver TransplantationVI: Split and Living Donor Transplantation47. Imaging Techniques for Partial Grafting48. Living Donor Transplantation in Children49. Living Donor Transplantation: Evaluation and Selection in Adults50. Adult Living Donor Right Hepatectomy and Recipient Operation51. Adult Living Donor Left Hepatectomy and Recipient Operation 52. Split Liver Transplantation for Pediatric and Adult Recipients53. Split Liver Transplantation for Two Adult Recipients54. Biliary and Vascular Reconstruction in Living Donor Transplantation55. Small-for-Size Syndrome56. Minimally Invasive Living Donor Hepatectomy57. Dual Grafts for Transplantation58. Outcomes of Living Donor Transplantation: The Western Perspective59. Outcomes of Living Donor Transplantation: The Eastern Perspective60. Ethics of Living Donor TransplantationVII: Unusual Operative Problems 61. Arterial Reconstruction Pitfalls62. Portal Vein Thrombosis and Other Venous Anomalies63. Combined Liver-Kidney Transplantation64. Retransplantation65. Clinical Management of Necrotic Liver Before and After Transplantation66. Intestinal and Multivisceral Transplantation67. Transplantation: Situs Inversus and Polysplenia Syndrome68. Auxiliary TransplantationVIII: Postoperative Care 69. Postoperative Intensive Care Management in Adults70. Postoperative Intensive Care Management in Children71. Postoperative Management Beyond the Intensive Care Unit: Adults72. Postoperative Care of Pediatric Transplant Recipients73. Transition of Pediatric Patients to Adulthood74. Renal Failure in Adults75. Graft Failure76. Technical Problems: Biliary77. Arterial Complications after Transplantation78. Infections After Transplantation79. Recurrent Hepatitis C After Transplantation80. Late Complications and Recurrence of Disease After Transplantation81. Neuropsychiatric Complications82. Neurological Complications83. Role of the Posttransplantation Clinical Nurse CoordinatorIX: Transplant Pathology 84. Histopathology of Liver Transplantation85. Pathology of NonNeoplastic Disease After Transplantation86. Transplant-Related MalignanciesX: Immunology of Liver Transplantation 87. Rejection After Transplantation88. Leukocyte Chimerism- Meaning and Consequences89. ABO, Tissue Typing, and Crossmatching Incompatibility90. Graft-Versus-Host DiseaseXI: Immunosuppression 91. Induction and Maintenance of Immunosuppression92. Special Considerations for Immunosuppression In Children93. Treatment of Acute and Chronic Rejection94. Novel Immunosuppression of Patients with Hepatic Malignancies95. Novel Immunosuppressive Drugs96. Immunosuppressive Biologic Agents97. Long-term Toxicity of Immunosuppressive TherapyXII: Survival and Results 98. Outcome Predictors in Transplantation99. U.S. Trends in Transplantation100. Long-term Functional Recovery and Quality of Life101. Survival and Quality of Life in ChildrenXIII: Future Developments in Liver Transplantation 102. Genetic and Genomic Potentials in Liver Transplantation103. Liver and Hepatocyte Xenotransplantation104. Stem Cell and Liver Regeneration105. Ischemia-Reperfusion Injury in Liver Transplantation106. Extracorporeal Perfusion for Resuscitation of Marginal Grafts107. Current Clinical Status of Extracorporeal Devices

2016 BMA Awards: Highly Commended, Surgical Specialties "Overall, the book should be an essential requirement in all liver transplantation units and be readily available to physicians and surgeons involved in liver transplantation at all stages in their training." --New England Journal of Medicine"This book is a rare gem - comprehensive, almost encyclopedic in scope, and highly authoritative with more than 200 medical doctors and other experts as contributors to its contents on  a highly complex and detailed medical and surgical specialty - liver transplantation. It is essential to have, for anyone in this field." -Nano Khilnani, BizIndia.net