The Axon

Structure, Function and Pathophysiology

Inbunden, Engelska, 1995

Av Stephen G. Waxman, Jeffery D. Kocsis, Peter K. Stys

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This book provides a comprehensive and up to date compendium that brings together contributions on the structure, function and pathophysiology of axons in both the peripheral and central nervous systems. Authoritative and superbly illustrated, the 33 chapters and introduction have been authored by 49 world-renowned authorities. New areas, such as the molecular biology of ion channels and of myelination, the role of calcium in pathophysiology and regeneration, cell adhesion molecules and their roles in axo-glial interactions and axonal guidance, and optical recording methods, are highlighted. A generously referenced book which will provide essential reference to those working in this field.

Produktinformation

Utgivningsdatum1995-05-25
Mått227 x 287 x 40 mm
Vikt2 272 g
FormatInbunden
SpråkEngelska
Antal sidor714
FörlagOUP USA
ISBN9780195082937

Tillhör följande kategorier

Anatomi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Neurologi och klinisk neurofysiologi inom Medicin

Introduction1: Sir A. Huxley: Electrical Activity of the Nerve: The Background up to 1952The Normal Axon2: C-H. Berthold and M. Rydmark: Morphology of Normal Peripheral Axons3: A. Hirano and J.F. Llena: Morphology of Central Nervous System Axons4: J.M. Ritchie: Physiology of Axons5: N. Kleitman and R.P. Bunge: The Schwann Cell: Morphology and Development6: J.A. Black, H.W. Sontheimer, and S.G. Waxman: The Oligodendrocyte, The Perinodal Astrocyte, and the Central Node of Ranvier7: E.S. Monuki and G.E. Lemke: Molecular Biology of Myelination8: J.L. Salzer: Mechanisms of Adhesion Between Axons and Glial Cells9: B. Grafstein: Axonal Transport: Function and Mechanisms10: R.W. Davenport, S. Bolsover, and S.B. Kater: Development of Axons: Calcium, Steering and the Growth Cone11: S.G. Waxman: Voltaged-gated Ion Channels in Axons: Localization, Function, and Development12: R.L. Barchi: Molecular Biology of Voltage-dependent Potassium and Sodium Channels13: W. Vogel and J.R. Schwartz: Voltage-clamp Studies in Axons: Macroscopic and Single Channel Currents14: J.D. Kocsis and K. Sakatani: Modulation of Axonal Excitability by Neurotransmitter Receptors15: P.K. Stys, S.G. Waxman, and B.R. Ransom: Ion Pumps and Exchangers16: H. Bostock: Mechanisms of Accommodation and adaptation in Myelinated Axons17: P.K. Stys and J.D. Kocsis: Electrophysiological Approaches to the Study of Axons18: P. Shrager: Action Potential Conduction Recorded Optically in Normal, Demyelinated and Remyelinating AxonsPrinciples of Axonal Pathophysiology19: G.W. Kreutzberg: Reactiono of the Neuronal Cell Body to Axonal Damage20: J.W. Griffin, et al.: Axonal Degeneration and Disorders of the Axonal Cytoskeleton21: J. Rosenbluth: Pathology of Demyelinated and Dysmyelinated Axons22: S.K. Ludwin: Pathology of the Myelin Sheath23: S.G. Waxman, J.D. Kocsis, and J.A. Black: Pathophysiology of Demyelinated Axons24: P.K. Stys, et al.: Anoxic-ischemic Injury in Axons25: O. Honmou and W. Young: Traumatic Injury of Spinal Axons26: J.T. Povlshock and C.W. Christman: Diffuse Axonal Injury27: M. Devor: Abnormal Excitability in Injured Axons28: M.A. Bisby: Regeneration of PNS Axons29: L. McKerracher, J.P. Julien, and A.J. Aguayo: Role of Cellular Interactions in Axonal Growth and Regeneration30: J. Kimura: Clinical Electrophysiology of PNS Axons31: S.J. Jones: Clinical Assessment of CNS Axons: Evoked Potentials32: A.R. Berger and H.H. Schaumburg: Human Peripheral Nerve Disease (Peripheral Neuropathies33: W.I. McDonald: Overview of Clinical Aspects of Multiple Sclerosis, Including Cognitive Deficit34: M.R. Dimitrijevic: Clinical Aspects of Traumatic Injury to CNS Axons

"A very nice compendium of current information about axonal histological structure, physiology and pathophysiology. There is an 'all star' cast of authors."--Canadian Journal of Neurological Sciences"The Axon: Structure, Function and Pathophysiology is an excellent addition to the field of axon physiology and pathophysiology. The book is well written and topics are thoroughly covered in a fashion suitable for both basic and clinical neuroscientists. The high-quality illustrations and photomicrographs and the succinct figure legends make it easy for readers to find and understand key points this book should become an important reference forpeople seeking a better understanding of axon biology."--New England Journal of Medicine"The illustrations are outstanding....The photomicrographs of nerves are the best that I have seen....The chapters are heavily referenced, with almost all having citations of articles from 1994 and even, in a chapter or two, 1995. This is unusual and remarkable. The authors have produced an encyclopedic reference book with material that is almost as up-to-date as a journal article....Waxman, Kocsis and Stys have edited an excellent reference volume that isup-to-date and extremely well illustrated. This is the sort of book that should be a standard in neurology and neurosurgery department libraries regardless of academic orientation. For departments ofophthamology and otolaryngology, this book is also a must."--Journal of the American Medical AssociationNoted, not reviewed, in Doody's Journal"An impressive book....with elegant descriptions....There are many stunning freeze-fracture and electron micrographs....The breadth of this book will improve knowledge about the axon for both basic and clinical scientists.This is to be welcomed."--Trends in Neurosciences