Sozdanie I Modifitsirovanie Biopolimernykh Matriksov Dlya Bioimplantov

Novaya strategiya sozdaniya iskusstvennykh tkaney iorganov putem biologicheskogo imitirovaniyasushchestvuyushchikh estestvennykh prototipov poluchaet vsebolee shirokoe razvitie. Vse bol'she razvivaetsyanapravlenie sozdaniya gibridnykh tkaney i organovsovremennymi metodami tkanevoy inzhenerii. Nesmotrya nauspekhi tkanevoy inzhenerii i bol'shoe kolichestvonakoplennykh eksperimental'nykh dannykh, mnogie protsessyvzaimodeystviya matriksov s kletkami izuchenynedostatochno polno.Na dannyy moment meditsina prakticheski ne ispol'zuetbiorezorbiruemye implanty, sozdannye na osnovematriksov iz polioksibutirata/polioksivalerata,obladayushchie odnosvyaznoy polimodal'noy vnutrenneystrukturoy v diapazone ot ~100 mkm do ~100 nm, sporistost'yu bolee 90%, modifitsirovannye kompleksnymplazmokhimicheskim i radiatsionno-khimicheskimvozdeystviem. Implanty s takimi kharakteristikaminaydut primenenie dlya resheniya mnogikh konkretnykh zadachv oblasti vosstanovitel'noy i zamestitel'noy khirurgii.