Del 2786 i serien Methods in Molecular Biology

RNA Vaccines

Methods and Protocols

Inbunden, Engelska, 2024

3 269 kr

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This second edition volume expands on the previous edition with discussions of the latest technology and advancements in the development of RNA vaccines and proposed solutions on how to tackle currently unmet medical needs.

Produktinformation

Utgivningsdatum2024-05-31
Mått178 x 254 x 28 mm
Vikt954 g
FormatInbunden
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor389
Upplaga2
FörlagSpringer-Verlag New York Inc.
ISBN9781071637692

Tillhör följande kategorier

Onkologi inom Medicin
Biokemisk teknik inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik

Introduction to RNA Vaccines Post COVID-19.- Self-Replicating RNA Derived from the Genomes of Positive Strand RNA Viruses.- Negative Strand RNA Virus Vectored Vaccines.- New Generation Self-Replicating RNA Vaccines Derived from Pestivirus Genome.- Trans-Amplifying RNA Vaccines Against Infectious Diseases: A Comparison with Non-Replicating and Self-Amplifying RNA.- Generation and Characterization of In Vitro Transcribed mRNA.- Production and Evaluation of Nucleoside-Modified mRNA Vaccines for Infectious Diseases.- Sequence-Optimized mRNA Vaccines Against Infectious Disease.- Design and Synthesis of Circular RNA Expression Vectors.- Electroporation of mRNA as a Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins.- A Basic Method for Formulating mRNA-Lipid Nanoparticle Vaccines in the Lab.- Messenger RNA Lipid-Based Nanoparticles: Optimization of Formulations in the Lab.- Plant Expression of Trans-Encapsidated Chimeric Viral Vaccines with Animal RNA Replicons: An Update.- Producing Plasmid DNA Template for Clinical Grade RNA Vaccine Manufacture.- Regulatory Considerations for Producing mRNA Vaccines for Clinical Trials.- Quality by Digital Design for Developing Platform RNA Vaccine Manufacturing Processes.- Nonclinical Safety Testing of RNA Vaccines.