Reverse Aging

Dr. Sandeep Kumar Singh is Assistant Professor in the All India Institute of Medical Sciences (AIIMS), Nagpur, India. He obtained his PhD in Biotechnology from Banaras Hindu University and conducted postdoctoral research in the Department of Neurobiology at the University of Chicago. Dr. Singh brings 17 years of experience in neuroscience, molecular biology, neurodegenerative diseases, aging, nutraceuticals, and nanomedicines. He is a member of several scientific societies, including the American Academy of Neurology, International Society of Neurochemistry, Society of Neurochemistry, Indian Academy of Neurosciences, and Alzheimer’s and related Disorders Society of India. Dr. Singh has published five books, including Elsevier’s A New Era in Alzheimer’s Research and Genome Editing for Neurodegenerative Diseases.Shailendra Kumar Mishra is co-founder of Indian Scientific Education and Technology (ISET) Foundation, a non-profit/non-governmental organization that persuades toward the science promotion. He is Molecular Human Genetics postgraduate, skilled in DNA Sequencing, Polymerase Chain Reaction (PCR), DNA & Plasmid isolation, Gel electrophoresis, Molecular hybridization, DNA elution from agarose gel, bacterial transformation, quantitation of DNA, DNA sequencing technique and versed in various diagnostic techniques. He did Master of Science in Molecular and Human Genetics from Jiwaji University, India, and research project from Banaras Hindu University, India. He has published his articles in some international and national journals such as Journal of Alzheimer’s Disease and Parkinsonism and Nature India. His major interest is to understand the aging process through molecular basis that could be beneficial to cure age-related diseases.

• 1 Aging: Concept, theories, principle and future prospective2 Overview of hallmarks of aging3 Reverse aging: Concept, significance, theories and future prospective4 Reprogramming a cell’s epigenetic status for reverse aging5 Cellular reprogramming for reverse aging6 NANOG: A key element for reverse aging7 Reduction of IGF‑1/PKA to promote hematopoietic‑stem cell‑based reverse aging8 Rejuvenating stem cells to reverse aging9 Histone modification (H3K27) to reverse aging10 Autophagy as a therapeutic target to enhance reverse aging11 mRNA enhanced cell therapy and reverse aging12 Reverse aging through immune driven signaling13 Mitochondrial modulations for reverse aging14 Reverse aging through cell cycle regulation15 Metabolic reprogramming for reverse aging16 Diets, phytochemicals, drugs, and nutraceuticals for reverse aging17 Artificial intelligence and antiaging research18 Reverse aging through redox‑sensitive transcription factors modulation