Redox State and Circadian Rhythms

Inbunden, Engelska, 2000

AvThérèse Vanden Driessche,J.L. Guisset,G.M. Petiau-de Vries

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This text addresses the redox balance in cells and organisms, which is of paramount importance in biology. In addition, a generally overseen circadian modulation is underlined. The balance involves, on the one hand, free radicals and reactive oxygen species and, on the other hand, scavengers capable of neutralizing their effects. This balance is crucial for life, since free radicals are required for some basic reactions (such as the activation of an enzyme involved in DNA synthesis) and since their excess leads to various toxic effects, most notably cancer. Different scavengers can be distributed at various times of the day, their amount possibly peaking at particular times. In fact, circadian rhythms may affect amounts of scavengers, amounts of foreseeable free radicals or the effects the latter can exert on a system. Free radicals are produced by some chains of normal metabolism. They are also produced by a variety of environmental stresses such as UV light, chemicals and drugs.

Produktinformation

Utgivningsdatum2000-08-31
Mått156 x 234 x 21 mm
Vikt617 g
FormatInbunden
SpråkEngelska
Antal sidor284
Upplaga2000
FörlagKluwer Academic Publishers
ISBN9780792364535

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'In summary, this is an excellent volume that I recommend without reservation to the biologist in all disciplines. It s rare to find a text of this nature that makes truly enjoyable reading. Not only is this volume packed with useful information, but it also conveys much of the enthusiasm and motivation of the authors in the pursuit of the advancement of science. As such it makes compelling reading in this volume would be an asset to any scientific library.' Annals of Botany 89:4 (2002)