Principles of Toxicology

Environmental and Industrial Applications

Inbunden, Engelska, 2022

AvStephen M. Roberts,Robert C. James,Phillip L. Williams

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Principles of Toxicology concisely and efficiently presents the scientific basis for toxicology as it applies to the workplace and the environment, covering diverse chemical hazards encountered in modern workplaces and natural environments and providing a practical understanding of these hazards for those concerned with protecting the health of humans and ecosystems. The work presents not only theory, but also practical information regarding chemical hazards to give the student and new professional a working knowledge of the practice of toxicology and the ability to solve problems in environmental and industrial settings. Case histories and examples from industrial and environmental exposures to chemicals are included to demonstrate the application of toxicological principles. To allow for seamless reader comprehension and further exploration of covered topics, the work is supplemented with numerous illustrations to clarify and summarize key points, as well as annotated bibliographies. In the 4th edition, all chapters and references have been updated to account for the latest scientific thinking, and new color figures have been added. New topics covered in 4th Edition of Principles of Toxicology include: Regulatory toxicology, including the key regulatory framework in which much of the field of toxicology operatesAlternative methods in toxicology, including cutting-edge approaches to developing new information on the toxicity of drugs and chemicalsThe dilemma of selecting safe exposure limits, guiding readers through practical considerations and pitfalls in developing and using safe exposure limits Ecological risk assessment, with detailed discussion of methods and considerations when evaluating the effects of contaminants on plants and animals.Providing information on the principles of toxicology and the application of those principles to solve problems in environmental and industrial settings, Principles of Toxicology serves as an excellent textbook resource for advanced undergraduate, graduate, and professional students in a range of environmental and health fields. It is also valuable to health professionals who need toxicological information and assistance beyond what is found in an introductory text to general toxicology.

Produktinformation

Utgivningsdatum2022-04-15
Mått218 x 274 x 31 mm
Vikt1 406 g
FormatInbunden
SpråkEngelska
Antal sidor592
Upplaga4
FörlagJohn Wiley & Sons Inc
ISBN9781119635178

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1 General Principles of ToxicologyRobert C. James, Stephen M. Roberts, and Phillip L. Williams2 Xenobiotic Absorption, Distribution, Metabolism and ExcretionMichael R. Franklin3 ToxicokineticsRebecca A. Clewell and Harvey J. Clewell III4 Regulatory ToxicologyRaymond M. David5 Alternative Methods in Toxicity TestingLeona D. Scanlan, XuefeiCao, and Christopher D. Vulpe6 ComputationalToxicologyRichard S. Judson, David M. Reif, Keith A. Houck, Thomas B. Knudsen, Joshua Harrill, Katie Paul Friedman7 Hematotoxicity:Toxic Effects on the Hematopoietic SystemLila Ramaiah, Tara Arndt, and Michelle Cora8 Hepatotoxicity: Toxic Effects on the LiveRobert C. James and Stephen M. Roberts9 Nephrotoxicity: Toxic Effects on the KidneyLawrence H. Lash10 Neurotoxicology: Toxic Effects on the Nervous SystemW. Michael Caudle, Meghan Bucher, Alexandria C. White, and Gary W. Miller11 Dermal Toxicology: Toxic Effects on the SkinSailesh Konda and Howard I Maibach12 Pulmonotoxicity: Toxic Effects on the Respiratory SystemCuiqing Liu and Qinghua Sun13 Immunotoxicity: Toxic Effects on the Immune SystemEric S. Sobel and Stephen M. Roberts14 Reproductive and Developmental Toxicity: Toxic Effects on the Female and Male Reproductive Tracts and OffspringShuo Xiao, Krista Symosko, and Charles A. Easley IV15 Mutagenesis and Genetic ToxicologyMartha M. Moore, Meagan B. Myers and Robert H. Heflich16 Chemical CarcinogenesisJames E. Klaunig, Luma Melo, and Karen Tilmant17 Properties and Effects of MetalsDavid B. Mayfield, Lisa A. Bailey, Joel M. Cohen, and Barbara D. Beck18 PesticidesJanice Britt19 Properties and Toxicology of Organic Solvents and Solvent-Like ChemicalsChristopher M. Teaf and Michele M. Garber20 NanotoxicologyHongbo Ma and Stephen M. Roberts21 Insights into EpidemiologyJ. Fryzek, C. Frankenfeld, N. Movva, L. Bylsma, and J. Acquavella22 Occupational and Environmental HealthLaura Breeher, Fredric Gerr, and T. Renėe Anthony23 Human Health Risk AssessmentLeah D. Stuchal24 Ecological Risk AssessmentBrett Thomas25 The Dilemma of Selecting Safe Exposure ValuesRobert C. James, Phillip L. Williams,and Stephen M. Roberts