Del 1106 i serien Advances in Experimental Medicine and Biology

Prefoldins: the new chaperones

Inbunden, Engelska, 2018

1 449 kr

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This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure.

Produktinformation

Utgivningsdatum2018-12-13
Mått178 x 254 x 14 mm
Vikt523 g
FormatInbunden
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor135
FörlagSpringer Nature Switzerland AG
ISBN9783030007362

Tillhör följande kategorier

Medicinsk genetik inom Medicin
Biologi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Nabil Djouder obtained his PhD in Molecular Pharmacology from the University of Strasbourg (France) and the University of Freiburg (Germany). In 2001 he moved to Basel (Switzerland) as a postdoctoral research fellow and joined the laboratory of W. Krek at the Novartis Friedrich Miescher Institute. In 2003 he became a member of the Competence Centre for Systems Physiology and Metabolic Diseases (CCSPMD) and in September 2009 he joined the CNIO as a Principal Investigator establishing his group in the field of Growth factors, Metabolism and Cancer.

Preface.- Structure of the molecular chaperone prefoldin.- Structure and function of archaeal prefoldin.- Role and functions of prefoldins.- Nuclear functions of prefoldins.- The yeast prefoldin Bud27.- URI-like prefoldin complex.- HSP90 and its R2TP/Prefoldin-like cochaperone.- Role and functions of URI: mouse models for URI.- Nuclear function of URI-like prefoldin complex.- URI and androgen regulation. Index.