PI3K and AKT Isoforms in Immunity

Mechanisms and Therapeutic Opportunities

Inbunden, Engelska, 2022

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This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease. PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration and cell death.

Produktinformation

Utgivningsdatum2022-10-16
Mått155 x 235 x 31 mm
Vikt875 g
FormatInbunden
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor466
FörlagSpringer International Publishing AG
ISBN9783031065651

Tillhör följande kategorier

Onkologi inom Medicin
Cellbiologi inom Naturvetenskap och teknik

Class I PI3K biology.- Class II PI3K biology.- Class III PI3K biology.- PTEN in immunity.- PHLPP Signaling in Immune Cells.- PHLPP Signaling in Immune Cells.- PI3K isoforms in cell signalling and innate immune cell responses.- AKT isoforms in macrophage activation, polarization and survival.- Control of CD4+ T cell Differentiation and Function by PI3K isoforms..- PI3K isoforms in CD8+ T cell development and function.- PI3K isoforms in B cells.- PI3K isoform signalling in platelets.- PI3K isoforms in vascular biology, a focus on the vascular system-immune response connection.- PI3K and AKT at the Interface of Signaling and Metabolism.- The Role of PI3K Isoforms in Autoimmune Disease.- AKT Isoforms in the Immune Response in Cancer.- PI3K isoform immunotherapy for solid tumours.- PI3K targeting in non-solid cancer.- AKT isoforms as a target in cancer and immunotherapy.- Developing PI3K Inhibitors for Respiratory Diseases.