Oncogene-Induced Senescence

This volume explores a collection of the most recent experimental approaches for the detection,modelling, characterization, and in-depth computational analysis of the biological phenomenon known as Oncogene-Induced Senescence (OIS). The chapters in this book cover topics such as protocols to study OIS in two-dimensional, three-dimensional, and in vivo (animal and human) settings; analyzing OIS using high-throughput bioinformatics; and discriminate OIS from aging. Published in the highly successfulMethods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting to avoid known pitfalls. Comprehensive and authoritative,Oncogene-Induced Senescence: Methods and Protocolsis a valuable resource for basic researchers and clinicians in the oncology field, and a great guide for computational scientists.