Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain. Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.

• 1. Fluorescence microscopy methods for the study of protein oligomerizationRoberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia2. Computational prediction and redesign of aberrant protein oligomerizationJaime Santos, Valentín Iglesias and Salvador Ventura3. Porphobilinogen synthase: An equilibrium of different assemblies in human healthEileen K. Jaffe4. Prediction and targeting of GPCR oligomer interfacesCarlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomersFrancesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas6. Exploring functional consequences of GPCR oligomerization requires a different lensKyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert7. Continuing challenges in targeting oligomeric GPCR-based drugsJoaquin Botta, Julia Appelhans and Peter J. McCormick8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectivesDiego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug actionFaron-Górecka Agata, Kuśmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta10. Oligomerization of G protein-coupled receptors: Still doubted?Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo

"This is a very important book that covers protein oligomerization in health and disease and provides essential knowledge of the oligomeric protein biology, which is critical to allow pharmacologic interventions in diseases associated with oligomeric protein malfunction. This is a unique book dedicated to fully explaining all about protein oligomerization." --Doody