Neuromodulation

The Biochemical Control of Neuronal Excitability

Inbunden, Engelska, 1987

AvLeonard K. Kaczmarek,Irwin B. Levitan,Leonard K. Kaczmarek,Irwin B. Levitan

1 159 kr

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This volume provides an introduction to the general principles of neuromodulation--the key neurobiological process for understanding how the brain works. Emphasizing ion channels and biochemical mechanisms of protein phosphorylation, the book shows how neurons regulate their intracellular calcium concentration by modulating the activity of certain ion channels. It goes on to explain the function of intracellular calcium and describes some fascinating neuromodulatory phenomena in the mammalian brain that have long awaited the kind of mechanistic investigations possible in simpler systems. Bridging the gap between neurochemistry and neurophysiology, the authors make complex concepts and research approaches comprehensible to scientists in either field.

Produktinformation

Utgivningsdatum1987-07-30
Mått156 x 234 x 17 mm
Vikt594 g
FormatInbunden
SpråkEngelska
Antal sidor304
FörlagOUP USA
ISBN9780195040975

Tillhör följande kategorier

1. What is Neuromodulation? ; 2. Ion Currents and Ion Channels, Substrates for Neuromodulation ; 3. Mechanisms and Modulation of Ion Channel Proteins ; 4. Biochemical Mechanisms in the Modulation of Ion Channel Function ; 5. Phosphorylation of Purified Ion Channel Proteins ; 6. Modulation of the Endogenous Rhythmic Bursting Activity in the Aplysia Neuron R15 ; 7. Modulation of Voltage-Dependent Potassium Currents During Long-Lasting Changes in Neuronal Activity ; 8. Modulation of Ion Channels Which are Regulated by Calcium ; 9. Modulation of Potassium Currents of Vertebrate Neurons ; 10. Modulation of a Potassium Channel in Aplysia Ssensory Neurons by Cyclic AMP-dependent Protein Phosphorylation ; 11. Modulation of Calcium Currents in Heart Cells and Neurons ; 12. Neurotransmitter Release and Its Modulation ; 13. Neuromodulation in the Mammalian Brain: The New Frontier