Molecular Basis of Neurological Disorders and Their Treatment

• 1 Towards a molecular model of the acetylcholine receptor channel.- 2 Proton-motive ATP synthase and energy transfer in the cell.- 3 Comparative analysis of the amount of subunit I and subunit IV of the cytochrome c oxidase mRNAs in the cerebral hemispheres of senescent rat and effect of acetyl-l-carnitine.- 4 Cytochemical and immunocytochemical investigation of respiratory complexes in individual fibres of human skeletal muscle.- 5 Native myelin proteins and myelin assembly in the central nervous system.- 6 Regulation of immune cells by serine phospholipids.- 7 Cell adhesion molecules belonging to the immunoglobulin superfamily.- 8 Neurogenic control of cerebral blood vessels.- 9 The fine structural aspects of brain oedema and associated microvascular and glial changes.- 10 Image-guided localized nuclear magnetic resonance spectroscopy of human brain tumours.- 11 Neuroimaging study of frontal lobes.- 12 Biochemical indicators of ischaemic brain damage.- 13 Molecular basis of astroglial reaction to brain injury; regulation of glial fibrillary acidic protein mRNA in rat cerebral cortex and in primary astroglial cell cultures.- 14 Tissue plasminogen activator; acute thrombotic stroke.- 15 Lysosomal storage of a mitochondrial protein in Batten’s disease (ceroid lipofuscinosis).- 16 Leber’s hereditary optic neuropathy; from the clinical to the new biochemical and molecular findings for understanding the pathogenesis of the disorder.- 17 Types and mechanism of mitochondrial DNA mutations in mitochondrial myopathy and related diseases.- 18 Direct tandem duplications of mitochondrial DNA in mitochondrial myopathy.- 19 Mutations of mitochondrial DNA; the molecular basis of mitochondrial encephalomyopathies and ageing.- 20 Analysis of giant deletions of human mitochondrialDNA in progressive external opthalmoplegia.- 21 Biochemical and genetic investigations in eleven cases of mitochondrial myopathies.- 22 Familiar cases of mitochondrial myopathies; mitochondrial DNA deletions and genetic analysis.- 23 The correlation between pathology, biochemistry and molecular genetics in mitochondrial encephalomyopathies.- 24 Various clinical presentation of mytochondriopathies; clinical and therapeutic considerations.- 25 Voltage-gated sodium channels as target for pharmacologic agents.- 26 A K+ channel opener in vascular smooth muscle; pharmacology and mechanism of action of cromakalim.- 27 Molecular and cellular mechanisms involves in high resistance neonatal brain resistance to anoxia.- 28 Metabolic activation and mechanisms of MPTP toxicity.- 29 Neurochemical changes produced by perinatal exposure to lead.- 30 Electrophoretic studies of the interaction of neuroleptic drugs with brain tissue.

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