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Modern Methods of Drug Design and Development

Inbunden, Engelska, 2023

Av Matthew Lloyd

2 909 kr

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Modern Methods of Drug Design and Development, a volume in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Recombinant protein purification for structural and kinetic studies, Steady-state kinetic analysis of reversible enzyme inhibitors, Steady-State Enzyme Kinetics, Analysis of enzyme kinetic data using ICEKAT, NMR techniques in drug discovery, Dynamic simulations and pre-steady state kinetics to guide drug discovery, Design and assay of substrate-product analogues for racemases and epimerases, Sensitive high throughput methods to screen for P450 inhibition: A- MI complex forming drugs, and more.

Other chapters cover Sensitive high throughput methods to screen for P450 inhibition: B-Heme loss causing drugs, Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis, Crystallographic fragment screening in academic cancer drug discovery, Fast fragment- and compound-screening pipeline at the Swiss Light Source, Chemical biology, enzymology and drug discovery, PROTACs, Proximity-Induced Pharmacology (PROTACs), and much more.



  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Enzymology series
  • Updated release includes the latest information on Modern Methods of Drug Design and Development

Produktinformation

  • Utgivningsdatum2023-10-17
  • Mått152 x 229 x undefined mm
  • Vikt1 070 g
  • FormatInbunden
  • SpråkEngelska
  • SerieMethods in Enzymology
  • Antal sidor598
  • FörlagElsevier Science
  • MedarbetareLloyd,Matthew
  • ISBN9780443158711