Microbial Systems Biology

• Flow Cytometry in Environmental Microbiology: A Rapid Approach for the Isolation of Single-Cells for Advanced Molecular Biology Analysis.-Pressure Cycling Technology in Systems Biology.-Targeted Isolation of Proteins from Natural Microbial Communities Living in an Extreme Environment.-Bacterial Identification and Subtyping Using DNA Microarray and DNA Sequencing.-Genetic Manipulation of the Obligate Chemolithoautotrophic Bacterium Thiobacillus denitrificans.-Genome-wide Mapping of the Binding Sites of Proteins that Interact with DNA.-MICROBIAL PROTEOMICS USING MASS SPECTROMETRY.-Fourier Transform Infrared Spectroscopy for Molecular Analysis of Microbial Cells.-Mass Spectrometry-based Microbial Metabolomics.-Fast Sampling of the Cellular Metabolome.-Metabolic Pathway Determination and Flux Analysis in Non-model Microorganisms through 13C-isotope Labeling.-Biolog Phenotype Microarrays.-NanoSIP: NanoSIMS Applications for Microbial Biology.-Electrophysiological-metabolic Modeling of Microbes: Applications in Fuel Cells and Environment Analysis.-Simulating Microbial Systems: Addressing Model Uncertainty/Incompleteness via Multiscale and Entropy Methods.-Bacterial Genome Annotation.-LeishCyc: a Guide to Building a Metabolic Pathway Database and the Visualization of Metabolomic Data.-Development of Constraint-base System-level Models of Microbial Metabolism.-Complex Network Analysis in Microbial Systems: Theory and Examples.-Modeling a Minimal Cell.

From the reviews:“This book … deals with one of the most dynamic trends in Biology, namely Systems Biology of Microorganisms. … Most of the chapters are of direct and immediate usefulness for scientists to start their own experiments with respect to different aspects of systems biology of a given microorganism or community/environment. … In my opinion, the purpose of this book … to introduce the reader to some of the established and state-of-the-art technologies that are being used to study microbial systems biology – is fully accomplished.” (Ioan I. Ardelean, Romanian Journal of Biochemistry, Vol. 50 (1), 2013)