Lipids and Membranes: Detection by Imaging and Lipidomics

Lipids are the cell's hydrophobic metabolites, and their self-assembly into bilayers creates membranes that are critical barriers and organizing platforms in cells. Lipids are a chemically diverse set of biological molecules subject to rapid metabolism and transport, and this dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the Volumes on Lipids and Membranes provide a broad snapshot of the state of the art of methods for studying biological lipids and biomembranes. This part focuses on methods for lipid detection both by lipidomics-based mass spectrometry and by imaging, including both small-molecule and genetically encoded probes.

• Provides readers with the latest advances in the biochemistry of lipids and biological membranes
• Focus on cutting-edge protocols by leaders in the disciplines of lipid and membrane chemistry, biochemistry, biophysics, and biology
• Covers approaches for lipid detection by imaging and lipidomics