This volume is an indispensable reference on the nature of immune defects in rodents and the special techniques necessary to maintain and breed them. The authors describe 64 inbred, hybrid, and mutant strains of rodents, each with some immune defect; explain mechanisms for ensuring genetic purity; and provide a standardized nomenclature for different varieties. Subsequent sections summarize and provide references on the genetics, pathophysiology, husbandry, and reproduction of each of the various strains as well as sound advice on planning for the selection, transportation, housing, and maintenance of these animals.
Committee on Immunologically Compromised Rodents, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
FRONT MATTER1 INTRODUCTION2 HEREDITARY IMMUNODEFICIENCIES3 INDUCED IMMUNODEFICIENCIES4 MAINTENANCE OF RODENTS REQUIRING ISOLATION5 MATING SYSTEMS FOR MUTANTS6 GENETIC MECHANISMS GOVERNING RESISTANCE OR SUSCEPTIBILITY . . .REFERENCESAPPENDIX: HEMATOPOIETIC CELL-SURFACE ANTIGENS MENTIONED IN THE TEXTGLOSSARYINDEX
National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Committee on Metagenomics: Challenges and Functional Applications
National Research Council, Division of Behavioral and Social Sciences and Education, Institute of Medicine, and Families Board on Children, Youth, Steve Olson
National Research Council, Division on Earth and Life Studies, Board on Agriculture and Natural Resources, Committee on Animal Nutrition, Subcommittee on Dog and Cat Nutrition
National Research Council, Division on Earth and Life Studies, Board on Agriculture and Natural Resources, Committee on Nutrient Requirements of Horses
National Research Council, Division of Behavioral and Social Sciences and Education, Commission on Behavioral and Social Sciences and Education, and Statistical Sciences Committee on AIDS Research and the Behavioral, Social, Lincoln E. Moses, Heather G. Miller, Charles F. Turner
National Research Council, Division on Engineering and Physical Sciences, and Applications Commission on Physical Sciences, Mathematics, Committee to Provide Interim Oversight of the DOE Nuclear Weapons Complex
National Research Council, Division on Earth and Life Studies, Environment and Resources Commission on Geosciences, Board on Environmental Studies and Toxicology, Committee to Review the Outer Continental Shelf Environmental Studies Program, Ecology Panel
National Research Council, Division on Engineering and Physical Sciences, Commission on Engineering and Technical Systems, Committee on Alternative Chemical Demilitarization Technologies
National Research Council, Commission on Life Sciences, Institute for Laboratory Animal Research, Committee on New and Emerging Models in Biomedical and Behavioral Research
National Research Council, Institute of Laboratory Animal Resources, Institute for Laboratory Animal Research, Commission on Life Sciences, Committee on Dogs
National Research Council, Division on Earth and Life Studies, Institute for Laboratory Animal Research, Commission on Life Sciences, Committee on Educational Programs in Laboratory Animal Science