Human Embryonic Stem Cells

Inbunden, Engelska, 2003

AvArlene Chiu,Mahendra S. Rao,Arlene Chiu,Mahendra S. Rao

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A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Produktinformation

Utgivningsdatum2003-08-01
Mått155 x 235 x 34 mm
Vikt926 g
FormatInbunden
SpråkEngelska
Antal sidor461
Upplaga2003
FörlagHumana Press Inc.
ISBN9781588293114

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Part I. Policy Ethical Issues Associated with Pluripotent Stem CellsSteve Usdin A Researcher's Guide to Federally Funded Human Embryonic Stem Cell Research in the United StatesGregory J. Downing Intellectual Property of Human Pluripotent Stem CellsMark L. Rohrbaugh Part II. Types of Pluripotent Cells Embryonal Carcinoma Cells: The Malignant Counterparts of ES and EG CellsJonathan S. Draper, Harry Moore, and Peter W. Andrews Human Pluripotent Cells from Bone MarrowFelipe Prosper and Catherine M. Verfaillie Protocols for the Isolation and Maintenance of Human Embryonic Stem CellsMelissa K. Carpenter, Chunhui Xu, Christine A. Daigh, Jessica E. Antosiewicz, and James A. Thomson Subcloning and Alternative Methods for the Derivation and Culture of Human Embryonic Stem CellsMichal Amit, Hanna Segev, Dorit Manor, and Joseph Itskovitz-Eldor Part III. Differentiation Differentiation of Neuroepithelia from Human Embryonic Stem CellsSu-Chun Zhang Pancreatic Differentiation of Pluripotent Stem CellsNadya Lumelsky Human Embryonic Stem Cell-Derived Cardiomyocytes: Derivation and CharacterizationChunhui Xu and Melissa K. Carpenter Vascular Lineage Differentiation from Human Embryonic Stem CellsSharon Gerecht Nir and Joseph Itskovitz-Eldor Hematopoietic Progenitors Derived from Human Embryonic Stem CellsDan S. Kaufman Part IV. Therapeutics Human Embryonic vs Adult Stem Cells for Transplantation TherapiesCalvin B. Harley and Mahendra S. Rao Genetic Manipulation of Human Embryonic Stem CellsMicha Drukker and Nissim Benvenisty Human Therapeutic CloningJose B. Cibelli Therapeutic Uses of Embryonic Stem CellsAlexander Kamb, Mani Ramaswami, and Mahendra S. Rao Human Embryonic Stem Cells and the Food and Drug Administration: Assuring the Safety of Novel Cellular TherapiesDonald W. Fink, Jr. Studies of a Human Neuron-Like Cell Line in Stroke and Spinal Cord Injury: Preclinical and Clinical PerspectivesPaul J. Reier, John Q. Trojanowski, Virginia M-Y. Lee, and Margaret J. Velardo Appendix I: Cell Lines and Companies Involved with Human Embryonic Stem Cell Research Appendix II: Useful Websites