Homologation Reactions

Vittorio Pace is Full Professor of Organic Chemistry at the University of Torino, Italy, since 2020. Before, he held a tenure-track professorship in Drug Synthesis at the University of Vienna, Austria. He received his habilitation (venia docendi) in Pharmaceutical Chemistry from the University of Vienna in 2016. He has been the recipient of different awards including the Ciamician Medal of the Italian Chemical Society, La Roche-Hoffmann Prize of the European Society of Medicinal Chemistry, the Thieme Award, and the Habilitation Award of the Austrian Chemical Society. Prof. Pace is an elected member of the Royal Spanish Academy of Pharmacy. His research is focused on the design and development of new synthetic concepts with functionalized organometallic reagents with a strong focus on homologation sequences.

• Foreword Preface AcknowledgmentsVOLUME 1Foreword Preface Acknowledgments   VOLUME I 1 Diazo-Mediated Homologation Reactions 2 Lithium Carbenoids in Homologation Chemistry  3 Streamlining C1 Homologation Reactions Using Continuous Flow Technology: Focus on Diazomethane and Methyllithium Chemistry  4 Magnesium Carbenoids in Homologation Chemistry 5 Homologation Reactions Based on Zinc Carbenoids and Related Reagents  6 Homologations via Carbene-Mediated Rearrangement Reactions 7 Oxenoids as Homologation Partners  8 Sulfur Ylides as C1 Homologating Reagents  9 Modern Homologation Reactions of Sulfoxonium Ylides via C-H Activation  10 Phosphorus Reagents for Two-, Three-, and Four-Carbon Homologation of Carbonyl Compounds to Functionalized Olefins  11 Homologation Tactics with Diborylmethane via alpha-Boryl Carbanions    VOLUME II 12 Homologation of Boronic Acids and Organoboranes by Transition-Metal-Free Reactions with Diazo Compounds and N-Sulfonylhydrazones 13 Stereospecific Reagent-Controlled Homologation Using Carbenoids Generated by Sulfoxide-Metal Exchange 14 Iterative Homologation of Boronic Esters: Assembly Line Synthesis 15 Fluorocarbon Chain Homologation and Elongation Reactions 16 Homologation Reactions for the Synthesis of Fluorinated Molecules 17 Synthesis of Oxiranes and Aziridines from Aldehydes and Imines Using Anionic Homologation Approaches 18 One-Carbon Homologation and Homologation-Functionalization Reactions of Aldehydes 19 Ring Expansion Homologation: Synthetic Strategies and Reaction Design 20 Dehomologations and Ring Contraction Strategies 21 Direct Radical C1 Homologations 22 Allenation of Terminal Alkynes for Allene Synthesis 23 Homogeneous Carbon Monoxide Homologation 24 Homologation Reactions with Carbon Dioxide 1 Diazo-Mediated Homologation Reactions 2 Lithium Carbenoids in Homologation Chemistry  3 Streamlining C1 Homologation Reactions Using Continuous Flow Technology: Focus on Diazomethane and Methyllithium Chemistry  4 Magnesium Carbenoids in Homologation Chemistry 5 Homologation Reactions Based on Zinc Carbenoids and Related Reagents  6 Homologations via Carbene-Mediated Rearrangement Reactions 7 Oxenoids as Homologation Partners  8 Sulfur Ylides as C1 Homologating Reagents  9 Modern Homologation Reactions of Sulfoxonium Ylides via C-H Activation  10 Phosphorus Reagents for Two-, Three-, and Four-Carbon Homologation of Carbonyl Compounds to Functionalized Olefins  11 Homologation Tactics with Diborylmethane via alpha-Boryl Carbanions    VOLUME 212 Homologation of Boronic Acids and Organoboranes by Transition-Metal-Free Reactions with Diazo Compounds and N-Sulfonylhydrazones 13 Stereospecific Reagent-Controlled Homologation Using Carbenoids Generated by Sulfoxide-Metal Exchange 14 Iterative Homologation of Boronic Esters: Assembly Line Synthesis 15 Fluorocarbon Chain Homologation and Elongation Reactions 16 Homologation Reactions for the Synthesis of Fluorinated Molecules 17 Synthesis of Oxiranes and Aziridines from Aldehydes and Imines Using Anionic Homologation Approaches 18 One-Carbon Homologation and Homologation-Functionalization Reactions of Aldehydes 19 Ring Expansion Homologation: Synthetic Strategies and Reaction Design 20 Dehomologations and Ring Contraction Strategies 21 Direct Radical C1 Homologations 22 Allenation of Terminal Alkynes for Allene Synthesis 23 Homogeneous Carbon Monoxide Homologation 24 Homologation Reactions with Carbon Dioxide